STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Amir_0675PFAM: Ppx/GppA phosphatase; KEGG: scl:sce1705 hypothetical protein. (320 aa)    
Predicted Functional Partners:
Amir_0673
PFAM: protein of unknown function DUF501; KEGG: csa:Csal_3040 hypothetical protein.
 
    0.952
Amir_5094
PFAM: Ppx/GppA phosphatase; KEGG: acp:A2cp1_0693 Ppx/GppA phosphatase.
  
  
0.948
Amir_6748
PFAM: Ppx/GppA phosphatase; KEGG: afw:Anae109_0702 Ppx/GppA phosphatase.
  
  
0.947
Amir_1698
(p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
 
 
 0.928
Amir_2268
PFAM: RelA/SpoT domain protein; KEGG: bha:BH1885 hypothetical protein.
     
  0.900
ppk
Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family.
 
  
 0.882
Amir_3296
PFAM: 3-dehydroquinate synthase; KEGG: gsu:GSU2025 3-dehydroquinate synthase.
 
 
    0.785
aroB
3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
 
 
    0.779
Amir_2000
3-dehydroquinate synthase; Catalyzes the conversion of sedoheptulose 7-phosphate to 2- epi-valiolone, which may serve as an alternative precursor for aminocyclitol biosynthesis.
 
 
    0.740
Amir_1900
PFAM: protein of unknown function DUF344; KEGG: tgr:Tgr7_0141 hypothetical protein.
 
  
 0.662
Your Current Organism:
Actinosynnema mirum
NCBI taxonomy Id: 446462
Other names: A. mirum DSM 43827, Actinosynnema mirum DSM 43827, Actinosynnema mirum str. DSM 43827, Actinosynnema mirum strain DSM 43827
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