STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Amir_0830PFAM: regulatory protein TetR; KEGG: mxa:MXAN_5545 transcriptional regulator, TetR family. (214 aa)    
Predicted Functional Partners:
Amir_6042
PFAM: Methionine synthase vitamin-B12 independent; KEGG: dal:Dalk_5194 hypothetical protein.
  
 
   0.543
Amir_0831
PFAM: alpha/beta hydrolase fold; KEGG: rsp:RSP_1258 putative hydrolase.
       0.540
pafA
Protein of unknown function DUF245 domain protein; Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side- chain amino group of a substrate lysine.
  
     0.472
Amir_0247
PFAM: NUDIX hydrolase; KEGG: rpd:RPD_3111 NUDIX hydrolase.
  
     0.469
Amir_2239
PFAM: protein of unknown function DUF245 domain protein; protein of unknown function DUF275 domain protein.
  
     0.457
Amir_0238
PFAM: Anion-transporting ATPase; KEGG: afw:Anae109_0972 chromosome partitioning-like ATPase.
  
     0.450
Amir_1335
KEGG: ccs:CCNA_02657 hypothetical protein.
  
     0.450
Amir_6756
Hypothetical protein.
  
     0.415
Amir_0832
Hypothetical protein.
       0.411
Your Current Organism:
Actinosynnema mirum
NCBI taxonomy Id: 446462
Other names: A. mirum DSM 43827, Actinosynnema mirum DSM 43827, Actinosynnema mirum str. DSM 43827, Actinosynnema mirum strain DSM 43827
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