STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Amir_1052KEGG: scl:sce2746 protein kinase. (371 aa)    
Predicted Functional Partners:
Amir_1051
TIGRFAM: DNA mismatch endonuclease Vsr; PFAM: DNA mismatch endonuclease vsr; KEGG: ajs:Ajs_2197 putative very short patch repair protein.
       0.606
Amir_1050
TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase; KEGG: sfu:Sfum_2797 DNA-cytosine methyltransferase.
  
  
 0.593
Amir_0716
KEGG: sal:Sala_0599 hypothetical protein.
  
     0.569
Amir_1053
Hypothetical protein.
       0.552
ruvC
Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.
     
 0.492
Amir_1049
KEGG: Hypothetical protein CBG18987.
       0.481
Amir_6080
KEGG: bpd:BURPS668_A3050 hypothetical protein.
  
     0.455
Amir_3164
Anti-sigma-factor antagonist; TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: mca:MCA1686 anti-sigma B factor antagonist; Belongs to the anti-sigma-factor antagonist family.
  
     0.447
Amir_1092
PFAM: CHAD domain containing protein; adenylate cyclase; KEGG: reh:H16_B1017 protein of the adenylate cyclase family.
 
     0.443
Amir_3237
Anti-sigma-factor antagonist; TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: sfu:Sfum_4033 anti-sigma-factor antagonist.
  
     0.429
Your Current Organism:
Actinosynnema mirum
NCBI taxonomy Id: 446462
Other names: A. mirum DSM 43827, Actinosynnema mirum DSM 43827, Actinosynnema mirum str. DSM 43827, Actinosynnema mirum strain DSM 43827
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.