STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ornExonuclease RNase T and DNA polymerase III; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family. (208 aa)    
Predicted Functional Partners:
rnj
Beta-lactamase domain protein; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
      
 0.695
Amir_3518
KEGG: ses:SARI_01345 ATP-dependent RNA helicase HrpA; TIGRFAM: ATP-dependent helicase HrpA; PFAM: helicase-associated domain protein; protein of unknown function DUF1605; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; AAA ATPase.
 
  
 0.689
Amir_7079
KEGG: hypothetical protein; TIGRFAM: tRNA adenylyltransferase; metal dependent phophohydrolase; PFAM: Polynucleotide adenylyltransferase region; metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
 
   
 0.646
rph
Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
  
  
 0.641
Amir_5831
PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; KEGG: pca:Pcar_1558 exopolyphosphatase related protein.
     
 0.619
Amir_1126
TIGRFAM: single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n; KEGG: ajs:Ajs_4211 single-strand binding protein.
 
 
 0.614
Amir_1186
Ribonuclease, Rne/Rng family; KEGG: sde:Sde_3188 RNAse G; TIGRFAM: ribonuclease, Rne/Rng family; PFAM: translation initiation factor IF-2 domain protein; SMART: RNA binding S1 domain protein.
  
  
 0.593
Amir_1333
2-oxo-acid dehydrogenase E1 subunit, homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
     0.526
Amir_1057
PFAM: major facilitator superfamily MFS_1; KEGG: mrd:Mrad2831_0079 major facilitator transporter.
       0.523
pnp
Guanosine pentaphosphate synthetase I/polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.
      
 0.506
Your Current Organism:
Actinosynnema mirum
NCBI taxonomy Id: 446462
Other names: A. mirum DSM 43827, Actinosynnema mirum DSM 43827, Actinosynnema mirum str. DSM 43827, Actinosynnema mirum strain DSM 43827
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