STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Amir_1060TIGRFAM: 1-phosphofructokinase; PFAM: PfkB domain protein; KEGG: gbm:Gbem_3234 1-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family. (308 aa)    
Predicted Functional Partners:
Amir_1061
Putative PTS IIA-like nitrogen-regulatory protein PtsN; TIGRFAM: PTS system, fructose subfamily, IIA subunit; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; KEGG: vco:VC0395_A1421 PTS system, fructose- specific IIABC component.
 
 0.999
Amir_1062
TIGRFAM: PTS system, fructose subfamily, IIC subunit; PTS system, fructose-specific, IIB subunnit; PFAM: phosphotransferase system PTS fructose- specific IIB subunit; phosphotransferase system EIIC; KEGG: rsh:Rsph17029_0435 PTS system, fructose subfamily, IIC subunit.
 
 0.999
Amir_1059
Transcriptional regulator, DeoR family; PFAM: regulatory protein DeoR; SMART: regulatory protein DeoR; KEGG: cak:Caul_0312 DeoR family transcriptional regulator.
 
  
 0.960
Amir_6917
Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.
  
 
 0.934
pfp
Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
  
  
 0.931
Amir_4944
PFAM: PfkB domain protein; KEGG: bha:BH0827 fructose 1-phosphate kinase.
  
  
 
0.927
Amir_0724
TIGRFAM: fructose-1,6-bisphosphatase, class II; PFAM: GlpX family protein; KEGG: dvm:DvMF_0188 fructose-1,6-bisphosphatase, class II.
     
 0.902
Amir_7069
Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
  
 0.793
Amir_5310
Transcriptional regulator, DeoR family; PFAM: regulatory protein DeoR; SMART: regulatory protein DeoR; KEGG: cak:Caul_0312 DeoR family transcriptional regulator.
 
  
 0.757
Amir_2223
PFAM: peptidase M50; KEGG: aeh:Mlg_1368 peptidase M50; Belongs to the peptidase M50B family.
  
    0.728
Your Current Organism:
Actinosynnema mirum
NCBI taxonomy Id: 446462
Other names: A. mirum DSM 43827, Actinosynnema mirum DSM 43827, Actinosynnema mirum str. DSM 43827, Actinosynnema mirum strain DSM 43827
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