STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Amir_1211PFAM: band 7 protein; SMART: band 7 protein; KEGG: sml:Smlt1263 putative transmembrane protein. (305 aa)    
Predicted Functional Partners:
Amir_1210
KEGG: sal:Sala_0218 hypothetical protein.
 
  
 0.990
ftsH
ATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
   
 0.882
Amir_2981
PFAM: protein of unknown function DUF1684; KEGG: acp:A2cp1_0109 protein of unknown function DUF1684.
 
   
 0.642
Amir_2110
PFAM: protein of unknown function DUF28; KEGG: gme:Gmet_0743 hypothetical protein.
 
 
    0.596
Amir_1212
Hypothetical protein.
       0.527
arc
AAA ATPase central domain protein; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
   
 
 0.495
Amir_0014
PFAM: Rhomboid family protein; KEGG: bsu:BSU24870 hypothetical protein.
   
 0.442
Amir_1014
PFAM: Rhomboid family protein; KEGG: amc:MADE_01334 rhomboid-like protein.
   
 0.442
Amir_5693
PFAM: ferredoxin-dependent glutamate synthase; glutamate synthase alpha subunit domain protein; glutamate synthase; glutamine amidotransferase class-II; KEGG: afw:Anae109_0854 glutamate synthase (ferredoxin).
     
 0.411
Amir_1209
PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: sfr:Sfri_0263 glyoxalase/bleomycin resistance protein/dioxygenase.
       0.409
Your Current Organism:
Actinosynnema mirum
NCBI taxonomy Id: 446462
Other names: A. mirum DSM 43827, Actinosynnema mirum DSM 43827, Actinosynnema mirum str. DSM 43827, Actinosynnema mirum strain DSM 43827
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