Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Amir_1237Adenylylsulfate reductase, thioredoxin dependent; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. (231 aa)    
Predicted Functional Partners:
Amir_1235
Sulfate adenylyltransferase, large subunit; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
 0.999
Amir_1239
Sulfite reductase (ferredoxin); PFAM: nitrite and sulphite reductase 4Fe-4S region; nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein; KEGG: aba:Acid345_2373 nitrite/sulfite reductase, hemoprotein beta-component, ferrodoxin-like.
 
 0.999
Amir_1236
TIGRFAM: sulfate adenylyltransferase, small subunit; PFAM: phosphoadenosine phosphosulfate reductase; KEGG: noc:Noc_2289 sulfate adenylyltransferase subunit 2.
  
 0.998
Amir_1238
Hypothetical protein.
  
  
 0.966
Amir_5854
TIGRFAM: uroporphyrin-III C-methyltransferase; siroheme synthase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: cvi:CV_0813 uroporphyrin-III C- methyltransferase.
 
  
 0.955
Amir_1231
PFAM: cobalamin (vitamin B12) biosynthesis CbiX protein; KEGG: cvi:CV_1567 precorrin-8X methylmutase.
 
  
 0.950
Amir_0225
PFAM: NADPH-dependent FMN reductase; KEGG: bpl:BURPS1106A_A1934 NADPH-dependent FMN reductase.
   
 
 0.914
Amir_0882
PFAM: NADPH-dependent FMN reductase; KEGG: cti:RALTA_A1785 NAD(P)H-dependent FMN reductase, sulfate starvation-induced protein.
   
 
 0.914
Amir_2285
PFAM: NADPH-dependent FMN reductase; KEGG: rsq:Rsph17025_0771 NADPH-dependent FMN reductase.
   
 
 0.914
Amir_6828
PFAM: Rhodanese domain protein; SMART: Rhodanese domain protein; KEGG: cja:CJA_2345 rhodanese-like domain protein.
    
 0.913
Your Current Organism:
Actinosynnema mirum
NCBI taxonomy Id: 446462
Other names: A. mirum DSM 43827, Actinosynnema mirum DSM 43827, Actinosynnema mirum str. DSM 43827, Actinosynnema mirum strain DSM 43827
Server load: low (14%) [HD]