STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Amir_2362KEGG: sus:Acid_3859 PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; PAS fold domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; PAS domain containing protein. (546 aa)    
Predicted Functional Partners:
Amir_2370
KEGG: dal:Dalk_3918 multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; Hpt domain protein; PAS fold- 4 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS domain containing protein.
 
 
0.999
Amir_5091
KEGG: ank:AnaeK_4253 GAF sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; GAF domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; GAF domain protein; histidine kinase HAMP region domain protein.
 
 
0.991
Amir_3739
PFAM: Stage II sporulation E family protein; response regulator receiver; SMART: response regulator receiver; protein phosphatase 2C domain protein; KEGG: pfo:Pfl01_3138 multi-sensor hybrid histidine kinase.
 
 
 0.926
Amir_1661
PFAM: MHYT domain protein; KEGG: sde:Sde_0524 putative integral membrane sensor protein.
 
    0.891
Amir_3736
Putative PAS/PAC sensor protein; KEGG: met:M446_3626 signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: Stage II sporulation E family protein; GAF domain protein; PAS fold-3 domain protein; Sulfate transporter/antisigma-factor antagonist STAS; PAS fold-4 domain protein; PAS fold domain protein; SMART: protein phosphatase 2C domain protein; PAC repeat-containing protein; GAF domain protein; PAS domain containing protein.
 
 
 0.838
Amir_3954
Multi-sensor signal transduction histidine kinase; KEGG: cti:RALTA_B0128 putative multi-site sensor histidine kinase; TIGRFAM: PAS sensor protein; PFAM: Stage II sporulation E family protein; response regulator receiver; PAS fold domain protein; PAS fold-4 domain protein; ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: response regulator receiver; protein phosphatase 2C domain protein; histidine kinase A domain protein; GAF domain protein; PAS domain containing protein; ATP-binding region ATPase domain protein.
 
 
0.837
Amir_2363
PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: rce:RC1_0432 KDP operon transcriptional regulatory protein KdpE.
  
 
 0.832
Amir_2346
TIGRFAM: flagellar motor switch protein FliG; PFAM: flagellar motor switch protein FliG; KEGG: bha:BH2457 flagellar motor switch protein G.
  
  
 0.795
flgK
TIGRFAM: flagellar hook-associated protein FlgK; PFAM: protein of unknown function DUF1078 domain protein; flagellar basal body rod protein; KEGG: ppd:Ppro_3455 flagellar hook-associated protein FlgK.
  
  
 0.786
Amir_2315
TIGRFAM: flagellar biosynthesis protein FlhA; PFAM: type III secretion FHIPEP protein; KEGG: bha:BH2438 flagellar biosynthesis protein FlhA.
  
  
 0.771
Your Current Organism:
Actinosynnema mirum
NCBI taxonomy Id: 446462
Other names: A. mirum DSM 43827, Actinosynnema mirum DSM 43827, Actinosynnema mirum str. DSM 43827, Actinosynnema mirum strain DSM 43827
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