STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Amir_2967PFAM: aminotransferase class I and II; KEGG: dvl:Dvul_2797 aminotransferase, class I and II. (384 aa)    
Predicted Functional Partners:
Amir_0702
Cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: afw:Anae109_3845 cystathionine gamma-lyase.
 
 
 0.954
Amir_5997
PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: sil:SPO3344 cystathionine gamma-lyase.
 
 
 0.946
Amir_2211
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
     
 0.928
Amir_4016
KEGG: sus:Acid_5487 O-acetylhomoserine/O- acetylserine sulfhydrylase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein; DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase.
   
 0.924
Amir_6240
O-acetylhomoserine/O-acetylserine sulfhydrylase; KEGG: bha:BH2603 O-acetylhomoserine aminocarboxypropyltransferase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein; aromatic amino acid beta-eliminating lyase/threonine aldolase.
   
 0.924
Amir_0700
Cystathionine beta-synthase; KEGG: afw:Anae109_3846 pyridoxal-5'-phosphate- dependent protein beta subunit; TIGRFAM: cystathionine beta-synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; CBS domain containing protein; SMART: CBS domain containing protein.
    
 0.918
Amir_3847
PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: dsh:Dshi_2951 pyridoxal-5'-phosphate- dependent protein beta subunit.
    
 0.911
Amir_6696
PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: sbp:Sbal223_2267 pyridoxal-5'-phosphate- dependent protein beta subunit.
    
 0.911
Amir_2691
PFAM: aminotransferase class I and II; KEGG: aeh:Mlg_2554 aminotransferase.
    
 0.909
Amir_6643
PFAM: aminotransferase class I and II; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: gur:Gura_2501 aminotransferase, class I and II.
    
0.909
Your Current Organism:
Actinosynnema mirum
NCBI taxonomy Id: 446462
Other names: A. mirum DSM 43827, Actinosynnema mirum DSM 43827, Actinosynnema mirum str. DSM 43827, Actinosynnema mirum strain DSM 43827
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