STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hldECytidyltransferase-related domain protein; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family. (488 aa)    
Predicted Functional Partners:
Amir_3671
PFAM: glycosyl transferase family 9; KEGG: rso:RSc0565 ADP-heptose--lipopolysaccharide heptosyltransferase II protein.
 
  
 0.956
Amir_3666
PFAM: Ankyrin; SMART: Ankyrin; KEGG: Os03g0655500; hypothetical protein.
 
     0.809
Amir_3667
PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase; KEGG: pca:Pcar_1259 ATP-binding transport protein; multicopy suppressor of HtrB.
       0.777
Amir_3665
Peptide-aspartate beta-dioxygenase; PFAM: Aspartyl/Asparaginyl beta-hydroxylase; KEGG: similar to aspartyl/asparaginyl beta- hydroxylase.
       0.776
Amir_3668
Peptide-aspartate beta-dioxygenase; PFAM: Aspartyl/Asparaginyl beta-hydroxylase; KEGG: hypothetical protein.
       0.776
Amir_3670
PFAM: Carbamoyltransferase; KEGG: bra:BRADO2235 putative carbamoyltransferase family protein.
 
     0.769
Amir_3672
PFAM: MbtH domain protein; KEGG: bbt:BBta_1084 hypothetical protein.
       0.600
Amir_3664
TIGRFAM: crotonyl-CoA reductase; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: dds:Ddes_1332 crotonyl-CoA reductase.
       0.574
Amir_3678
PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; Male sterility domain; KEGG: aba:Acid345_0895 NAD-dependent epimerase/dehydratase.
 
  
 0.539
Amir_4408
PFAM: glycosyl transferase group 1; KEGG: cti:RALTA_A0583 putative glycosyl transferase, group 1.
 
   
 0.487
Your Current Organism:
Actinosynnema mirum
NCBI taxonomy Id: 446462
Other names: A. mirum DSM 43827, Actinosynnema mirum DSM 43827, Actinosynnema mirum str. DSM 43827, Actinosynnema mirum strain DSM 43827
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.