STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Amir_3853Anti-sigma-factor antagonist; TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: mca:MCA1686 anti-sigma B factor antagonist; Belongs to the anti-sigma-factor antagonist family. (112 aa)    
Predicted Functional Partners:
Amir_3736
Putative PAS/PAC sensor protein; KEGG: met:M446_3626 signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: Stage II sporulation E family protein; GAF domain protein; PAS fold-3 domain protein; Sulfate transporter/antisigma-factor antagonist STAS; PAS fold-4 domain protein; PAS fold domain protein; SMART: protein phosphatase 2C domain protein; PAC repeat-containing protein; GAF domain protein; PAS domain containing protein.
 
 
 0.898
Amir_3852
KEGG: rle:RL0999 putative two-component regulator sensor histidine kinase protein; TIGRFAM: PAS sensor protein; PFAM: Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein.
 
   0.883
Amir_3954
Multi-sensor signal transduction histidine kinase; KEGG: cti:RALTA_B0128 putative multi-site sensor histidine kinase; TIGRFAM: PAS sensor protein; PFAM: Stage II sporulation E family protein; response regulator receiver; PAS fold domain protein; PAS fold-4 domain protein; ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: response regulator receiver; protein phosphatase 2C domain protein; histidine kinase A domain protein; GAF domain protein; PAS domain containing protein; ATP-binding region ATPase domain protein.
  
 
 0.876
Amir_3741
Putative anti-sigma regulatory factor, serine/threonine protein kinase; PFAM: Stage II sporulation E family protein; ATP- binding region ATPase domain protein; SMART: protein phosphatase 2C domain protein; KEGG: mch:Mchl_3342 putative anti-sigma regulatory factor, serine/threonine protein kinase.
  
 
 0.823
Amir_2370
KEGG: dal:Dalk_3918 multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; Hpt domain protein; PAS fold- 4 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS domain containing protein.
  
  
 0.800
Amir_3851
PFAM: alpha/beta hydrolase fold; KEGG: rle:RL1000 putative hydrolase.
       0.773
Amir_5399
TIGRFAM: RNA polymerase sigma-70 factor, sigma- B/F/G subfamily; RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 4 domain protein; sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; sigma- 70 region 3 domain protein; KEGG: bha:BH0529 RNA polymerase sigma factor SigB.
 
   0.616
Amir_5363
TIGRFAM: RNA polymerase sigma-70 factor, sigma- B/F/G subfamily; RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; sigma-70 region 3 domain protein; Sigma-70 region 4 type 2; sigma- 70 region 4 domain protein; KEGG: bha:BH0529 RNA polymerase sigma factor SigB.
 
   0.605
Amir_5092
Anti-sigma-factor antagonist; TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: mca:MCA1686 anti-sigma B factor antagonist; Belongs to the anti-sigma-factor antagonist family.
  
     0.534
Amir_5033
PFAM: Stage II sporulation E family protein; response regulator receiver; SMART: protein phosphatase 2C domain protein; response regulator receiver; KEGG: mag:amb3537 serine phosphatase RsbU, regulator of sigma subunit.
  
   0.510
Your Current Organism:
Actinosynnema mirum
NCBI taxonomy Id: 446462
Other names: A. mirum DSM 43827, Actinosynnema mirum DSM 43827, Actinosynnema mirum str. DSM 43827, Actinosynnema mirum strain DSM 43827
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