STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Amir_3883PFAM: condensation domain protein; KEGG: bam:Bamb_1537 amino acid adenylation domain- containing protein. (406 aa)    
Predicted Functional Partners:
Amir_4604
TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; Beta- ketoacyl synthase; Alcohol dehydrogenase GroES domain protein; short-chain dehydrogenase/reductase SDR; condensation domain protein; Acyl transferase; KR domain protein; Alcohol dehydrogenase zinc-binding domain protein; Thioesterase; phosphopantetheine-binding; KEGG: pae:PA3327 non-ribosomal peptide synthetase.
  
  
 0.911
Amir_3892
TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; Beta- ketoacyl synthase; short-chain dehydrogenase/reductase SDR; condensation domain protein; KR domain protein; Thioesterase; phosphopantetheine-binding; KEGG: pen:PSEEN2718 polyketide synthase (terminal component).
  
  
 0.890
Amir_4698
TIGRFAM: thioester reductase domain protein; PFAM: Male sterility domain; short-chain dehydrogenase/reductase SDR; Beta-ketoacyl synthase; 3- beta hydroxysteroid dehydrogenase/isomerase; Acyl transferase; KR domain protein; Erythronolide synthase docking; phosphopantetheine-binding; NAD-dependent epimerase/dehydratase; KEGG: pst:PSPTO_4687 coronafacic acid polyketide synthetase II.
  
  
 0.759
Amir_2684
PFAM: short-chain dehydrogenase/reductase SDR; Beta- ketoacyl synthase; Acyl transferase; KR domain protein; Erythronolide synthase docking; Thioesterase; NAD- dependent epimerase/dehydratase; phosphopantetheine- binding; KEGG: met:M446_0170 beta-ketoacyl synthase.
  
  
 0.734
Amir_3602
Cyclic nucleotide-binding protein; TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; Methyltransferase type 11; Methyltransferase type 12; Thioesterase; phosphopantetheine-binding; condensation domain protein; KEGG: smd:Smed_6472 amino acid adenylation domain.
  
  
 0.694
Amir_4440
TIGRFAM: thioester reductase domain protein; PFAM: short-chain dehydrogenase/reductase SDR; Beta- ketoacyl synthase; Male sterility domain; KR domain protein; Acyl transferase; Erythronolide synthase docking; phosphopantetheine-binding; NAD-dependent epimerase/dehydratase; KEGG: eca:ECA0602 type I polyketide synthase.
  
  
 0.684
Amir_3294
PFAM: Acyl transferase; AMP-dependent synthetase and ligase; Beta-ketoacyl synthase; Alcohol dehydrogenase GroES domain protein; short-chain dehydrogenase/reductase SDR; KR domain protein; Alcohol dehydrogenase zinc-binding domain protein; NAD-dependent epimerase/dehydratase; phosphopantetheine-binding; KEGG: pst:PSPTO_4686 coronafacic acid polyketide synthase I.
  
  
 0.665
Amir_3577
TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; Thioesterase; phosphopantetheine-binding; condensation domain protein; KEGG: mxa:MXAN_3618 non-ribosomal peptide synthetase.
  
  
 0.648
Amir_3891
TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; Thioesterase; phosphopantetheine-binding; condensation domain protein; KEGG: pen:PSEEN2717 non-ribosomal peptide synthetase.
  
  
 0.648
Amir_4498
TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; Thioesterase; phosphopantetheine-binding; condensation domain protein; KEGG: mxa:MXAN_3618 non-ribosomal peptide synthetase.
  
  
 0.648
Your Current Organism:
Actinosynnema mirum
NCBI taxonomy Id: 446462
Other names: A. mirum DSM 43827, Actinosynnema mirum DSM 43827, Actinosynnema mirum str. DSM 43827, Actinosynnema mirum strain DSM 43827
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