STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lntApolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily. (518 aa)    
Predicted Functional Partners:
Amir_3402
PFAM: glycosyl transferase family 2; KEGG: ank:AnaeK_2710 glycosyl transferase family 2.
    
 0.922
Amir_4836
PFAM: glycosyl transferase family 2; KEGG: gbm:Gbem_1276 glycosyl transferase family 2.
    
 0.798
lspA-2
Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.
 
   
 0.791
lgt
Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.
 
   
 0.780
secF
Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily.
     
 0.570
Amir_4186
Hypothetical protein; KEGG: met:M446_3732 von Willebrand factor type A.
       0.535
Amir_1378
KEGG: tbd:Tbd_0827 DNA polymerase III, epsilon subunit; TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease RNase T and DNA polymerase III; Excinuclease ABC C subunit domain protein; SMART: Exonuclease; Excinuclease ABC C subunit domain protein.
 
   
 0.525
Amir_7082
PFAM: virulence factor MVIN family protein; KEGG: glo:Glov_2048 integral membrane protein MviN.
 
   
 0.509
Amir_2110
PFAM: protein of unknown function DUF28; KEGG: gme:Gmet_0743 hypothetical protein.
 
     0.477
glyS
glycyl-tRNA synthetase, beta subunit; KEGG: hypothetical protein; K01878 glycyl-tRNA synthetase alpha chain; TIGRFAM: glycyl-tRNA synthetase, beta subunit; glycyl-tRNA synthetase, alpha subunit; PFAM: glycyl-tRNA synthetase alpha subunit; glycyl- tRNA synthetase beta subunit.
       0.475
Your Current Organism:
Actinosynnema mirum
NCBI taxonomy Id: 446462
Other names: A. mirum DSM 43827, Actinosynnema mirum DSM 43827, Actinosynnema mirum str. DSM 43827, Actinosynnema mirum strain DSM 43827
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.