STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Amir_4407Anti-sigma-factor antagonist; TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: swi:Swit_1492 anti-sigma-factor antagonist. (127 aa)    
Predicted Functional Partners:
Amir_3954
Multi-sensor signal transduction histidine kinase; KEGG: cti:RALTA_B0128 putative multi-site sensor histidine kinase; TIGRFAM: PAS sensor protein; PFAM: Stage II sporulation E family protein; response regulator receiver; PAS fold domain protein; PAS fold-4 domain protein; ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: response regulator receiver; protein phosphatase 2C domain protein; histidine kinase A domain protein; GAF domain protein; PAS domain containing protein; ATP-binding region ATPase domain protein.
 
 
 0.909
Amir_3736
Putative PAS/PAC sensor protein; KEGG: met:M446_3626 signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: Stage II sporulation E family protein; GAF domain protein; PAS fold-3 domain protein; Sulfate transporter/antisigma-factor antagonist STAS; PAS fold-4 domain protein; PAS fold domain protein; SMART: protein phosphatase 2C domain protein; PAC repeat-containing protein; GAF domain protein; PAS domain containing protein.
 
 
 0.891
Amir_3741
Putative anti-sigma regulatory factor, serine/threonine protein kinase; PFAM: Stage II sporulation E family protein; ATP- binding region ATPase domain protein; SMART: protein phosphatase 2C domain protein; KEGG: mch:Mchl_3342 putative anti-sigma regulatory factor, serine/threonine protein kinase.
  
 
 0.823
Amir_2370
KEGG: dal:Dalk_3918 multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; Hpt domain protein; PAS fold- 4 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS domain containing protein.
  
  
 0.800
Amir_4406
Hypothetical protein.
       0.697
Amir_5361
Putative anti-sigma regulatory factor, serine/threonine protein kinase; PFAM: ATP-binding region ATPase domain protein; KEGG: dvm:DvMF_0253 putative signal transduction histidine kinase.
  
   0.617
Amir_1818
Putative signal transduction histidine kinase.
  
   0.600
Amir_1819
Anti-sigma-factor antagonist; TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: pde:Pden_0820 anti-sigma-factor antagonist.
  
     0.593
Amir_4405
Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: reh:H16_A3378 transcriptional regulator, AraC- family.
       0.528
Amir_2807
Anti-sigma-factor antagonist; TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: mag:amb0333 anti-anti-sigma regulatory factor.
  
     0.512
Your Current Organism:
Actinosynnema mirum
NCBI taxonomy Id: 446462
Other names: A. mirum DSM 43827, Actinosynnema mirum DSM 43827, Actinosynnema mirum str. DSM 43827, Actinosynnema mirum strain DSM 43827
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