STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Amir_4436PFAM: amine oxidase; FAD dependent oxidoreductase; KEGG: reh:H16_A0856 L-amino-acid oxidase. (480 aa)    
Predicted Functional Partners:
Amir_1468
PFAM: histone deacetylase superfamily; KEGG: bha:BH3237 acetoin dehydrogenase.
    
 0.728
Amir_6515
PFAM: histone deacetylase superfamily; KEGG: HDA08; HDA08 (histone deacetylase 8); histone deacetylase.
    
 0.728
Amir_6457
Hypothetical protein; KEGG: eln1; tropoelastin 1.
  
     0.502
Amir_3811
PFAM: Squalene/phytoene synthase; KEGG: PSY; PSY (PHYTOENE SYNTHASE); geranylgeranyl- diphosphate geranylgeranyltransferase; K02291 phytoene synthase.
   
  
 0.491
Amir_1047
Non-specific serine/threonine protein kinase; KEGG: scl:sce3369 SWF/SNF family helicase; PFAM: SNF2-related protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein.
    
 0.481
Amir_4127
PFAM: SNF2-related protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; KEGG: scl:sce2990 hypothetical protein.
    
 0.481
Amir_4128
PFAM: helicase domain protein; SNF2-related protein; type III restriction protein res subunit; SMART: helicase domain protein; DEAD-like helicase; KEGG: xau:Xaut_2988 helicase domain-containing protein.
    
 0.481
Amir_0081
KEGG: xau:Xaut_1560 phenylacetaldoxime dehydratase.
  
     0.469
Amir_0002
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
    0.418
Amir_0251
KEGG: sus:Acid_0002 DNA polymerase III, beta subunit; TIGRFAM: DNA polymerase III, beta subunit; PFAM: DNA polymerase III beta chain; SMART: DNA polymerase III beta chain.
   
    0.418
Your Current Organism:
Actinosynnema mirum
NCBI taxonomy Id: 446462
Other names: A. mirum DSM 43827, Actinosynnema mirum DSM 43827, Actinosynnema mirum str. DSM 43827, Actinosynnema mirum strain DSM 43827
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.