STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Amir_4699Mycocerosate synthase., Erythronolide synthase; PFAM: Acyl transferase; short-chain dehydrogenase/reductase SDR; Beta-ketoacyl synthase; KR domain protein; phosphopantetheine-binding; KEGG: met:M446_0170 beta-ketoacyl synthase. (4080 aa)    
Predicted Functional Partners:
Amir_4003
Oleoyl-(acyl-carrier-protein) hydrolase; PFAM: Thioesterase; KEGG: pau:PA14_09230 pyochelin biosynthetic protein PchC.
    0.769
Amir_4698
TIGRFAM: thioester reductase domain protein; PFAM: Male sterility domain; short-chain dehydrogenase/reductase SDR; Beta-ketoacyl synthase; 3- beta hydroxysteroid dehydrogenase/isomerase; Acyl transferase; KR domain protein; Erythronolide synthase docking; phosphopantetheine-binding; NAD-dependent epimerase/dehydratase; KEGG: pst:PSPTO_4687 coronafacic acid polyketide synthetase II.
 
 
0.765
Amir_2678
Oleoyl-(acyl-carrier-protein) hydrolase; PFAM: Thioesterase; KEGG: bpd:BURPS668_A0873 pyochelin biosynthetic protein PchC.
    0.757
Amir_4493
PFAM: Thioesterase; KEGG: mxa:MXAN_4290 putative thioesterase.
    0.694
Amir_4359
PFAM: Acyl transferase; KR domain protein; Beta- ketoacyl synthase; short-chain dehydrogenase/reductase SDR; NAD-dependent epimerase/dehydratase; phosphopantetheine-binding; KEGG: mxa:MXAN_4527 polyketide synthase.
 
 
0.629
Amir_2683
PFAM: Acyl transferase; Beta-ketoacyl synthase; short-chain dehydrogenase/reductase SDR; Male sterility domain; KR domain protein; Erythronolide synthase docking; NAD-dependent epimerase/dehydratase; phosphopantetheine- binding; KEGG: mxa:MXAN_4527 polyketide synthase.
 
 
0.603
Amir_3294
PFAM: Acyl transferase; AMP-dependent synthetase and ligase; Beta-ketoacyl synthase; Alcohol dehydrogenase GroES domain protein; short-chain dehydrogenase/reductase SDR; KR domain protein; Alcohol dehydrogenase zinc-binding domain protein; NAD-dependent epimerase/dehydratase; phosphopantetheine-binding; KEGG: pst:PSPTO_4686 coronafacic acid polyketide synthase I.
 
 
0.600
Amir_3892
TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; Beta- ketoacyl synthase; short-chain dehydrogenase/reductase SDR; condensation domain protein; KR domain protein; Thioesterase; phosphopantetheine-binding; KEGG: pen:PSEEN2718 polyketide synthase (terminal component).
 
 
0.593
Amir_2682
PFAM: short-chain dehydrogenase/reductase SDR; Beta- ketoacyl synthase; Acyl transferase; KR domain protein; Erythronolide synthase docking; NAD-dependent epimerase/dehydratase; phosphopantetheine-binding; KEGG: mxa:MXAN_4527 polyketide synthase.
 
 
0.583
Amir_3682
PFAM: KR domain protein; Beta-ketoacyl synthase; Acyl transferase; short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; KEGG: mxa:MXAN_3631 polyketide synthase type I.
 
 
0.579
Your Current Organism:
Actinosynnema mirum
NCBI taxonomy Id: 446462
Other names: A. mirum DSM 43827, Actinosynnema mirum DSM 43827, Actinosynnema mirum str. DSM 43827, Actinosynnema mirum strain DSM 43827
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.