STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Amir_4912TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; condensation domain protein; KEGG: mxa:MXAN_4414 non-ribosomal peptide synthase. (1715 aa)    
Predicted Functional Partners:
Amir_4911
PFAM: Beta-ketoacyl synthase; KR domain protein; Acyl transferase; short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; KEGG: mxa:MXAN_3620 polyketide synthase type I.
 0.997
Amir_2683
PFAM: Acyl transferase; Beta-ketoacyl synthase; short-chain dehydrogenase/reductase SDR; Male sterility domain; KR domain protein; Erythronolide synthase docking; NAD-dependent epimerase/dehydratase; phosphopantetheine- binding; KEGG: mxa:MXAN_4527 polyketide synthase.
 0.989
Amir_3682
PFAM: KR domain protein; Beta-ketoacyl synthase; Acyl transferase; short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; KEGG: mxa:MXAN_3631 polyketide synthase type I.
 0.988
Amir_2682
PFAM: short-chain dehydrogenase/reductase SDR; Beta- ketoacyl synthase; Acyl transferase; KR domain protein; Erythronolide synthase docking; NAD-dependent epimerase/dehydratase; phosphopantetheine-binding; KEGG: mxa:MXAN_4527 polyketide synthase.
 0.985
Amir_2695
PFAM: short-chain dehydrogenase/reductase SDR; Beta- ketoacyl synthase; Male sterility domain; Acyl transferase; KR domain protein; phosphopantetheine- binding; NAD-dependent epimerase/dehydratase; KEGG: met:M446_0170 beta-ketoacyl synthase.
  
 0.982
Amir_4359
PFAM: Acyl transferase; KR domain protein; Beta- ketoacyl synthase; short-chain dehydrogenase/reductase SDR; NAD-dependent epimerase/dehydratase; phosphopantetheine-binding; KEGG: mxa:MXAN_4527 polyketide synthase.
 
 0.969
Amir_3892
TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; Beta- ketoacyl synthase; short-chain dehydrogenase/reductase SDR; condensation domain protein; KR domain protein; Thioesterase; phosphopantetheine-binding; KEGG: pen:PSEEN2718 polyketide synthase (terminal component).
 
0.967
Amir_4914
PFAM: condensation domain protein; KEGG: mxa:MXAN_4525 non-ribosomal peptide synthase MxaA.
   0.953
Amir_3674
PFAM: AMP-dependent synthetase and ligase; nitroreductase; phosphopantetheine-binding; KEGG: pen:PSEEN2716 non-ribosomal peptide synthetase.
 
 
0.922
Amir_3675
TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; Non-ribosomal peptide synthetase; condensation domain protein; KEGG: psb:Psyr_1792 amino acid adenylation.
 
 
0.921
Your Current Organism:
Actinosynnema mirum
NCBI taxonomy Id: 446462
Other names: A. mirum DSM 43827, Actinosynnema mirum DSM 43827, Actinosynnema mirum str. DSM 43827, Actinosynnema mirum strain DSM 43827
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