STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Amir_5004PFAM: regulatory protein AsnC/Lrp family; SMART: regulatory protein AsnC/Lrp family; KEGG: har:HEAR0121 leucine-responsive regulatory protein. (162 aa)    
Predicted Functional Partners:
Amir_2542
PFAM: regulatory protein AsnC/Lrp family; SMART: regulatory protein AsnC/Lrp family; KEGG: aha:AHA_0491 AsnC family transcriptional regulator.
  
     0.768
Amir_5003
KEGG: ank:AnaeK_1422 pyruvate dehydrogenase (acetyl- transferring); TIGRFAM: pyruvate dehydrogenase (acetyl- transferring) E1 component, alpha subunit; PFAM: dehydrogenase E1 component.
       0.600
Amir_5001
PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain- containing protein; E3 binding domain protein; KEGG: bpt:Bpet3509 branched-chain alpha-keto acid dehydrogenase subunit E2.
       0.492
Amir_5002
PFAM: Transketolase central region; Transketolase domain protein; KEGG: nha:Nham_3108 transketolase, central region.
       0.464
Amir_5693
PFAM: ferredoxin-dependent glutamate synthase; glutamate synthase alpha subunit domain protein; glutamate synthase; glutamine amidotransferase class-II; KEGG: afw:Anae109_0854 glutamate synthase (ferredoxin).
     
 0.420
HDA1511
KEGG: HDA1511; class II RPD3 type histone deacetylase protein; K11407 histone deacetylase 6/10.
       0.409
Amir_5000
PFAM: GCN5-related N-acetyltransferase; KEGG: pla:Plav_1643 GCN5-related N- acetyltransferase.
       0.409
Your Current Organism:
Actinosynnema mirum
NCBI taxonomy Id: 446462
Other names: A. mirum DSM 43827, Actinosynnema mirum DSM 43827, Actinosynnema mirum str. DSM 43827, Actinosynnema mirum strain DSM 43827
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