STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Amir_5122PFAM: PfkB domain protein; KEGG: sme:SM_b21462 putative sugar kinase protein. (347 aa)    
Predicted Functional Partners:
Amir_1458
PFAM: glycoside hydrolase family 4; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: sus:Acid_1925 glycoside hydrolase family protein.
 
     0.779
Amir_5123
RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; sigma-70 region 4 domain protein; KEGG: pla:Plav_0951 ECF subfamily RNA polymerase sigma-24 factor.
       0.757
Amir_6847
PFAM: Myo-inositol catabolism IolB domain protein; KEGG: sus:Acid_1480 myo-inositol catabolism IolB domain-containing protein.
 
  
 0.733
Amir_6846
PFAM: thiamine pyrophosphate protein central region; thiamine pyrophosphate protein domain protein TPP- binding; thiamine pyrophosphate protein TPP binding domain protein; KEGG: bid:Bind_2834 thiamine pyrophosphate protein central region; Belongs to the TPP enzyme family.
 
  
 0.635
Amir_6848
PFAM: PfkB domain protein; KEGG: sus:Acid_1481 ribokinase-like domain- containing protein.
  
     0.537
Amir_6852
PFAM: Xylose isomerase domain protein TIM barrel; KEGG: sit:TM1040_3346 xylose isomerase-like TIM barrel.
 
  
 0.524
hisA
Bifunctional HisA/TrpF protein; KEGG: plu:plu0797 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4- carboxamide isomerase; TIGRFAM: bifunctional HisA/TrpF protein; PFAM: histidine biosynthesis protein.
  
  
 0.513
Amir_5121
PFAM: glycosyl transferase family 51; penicillin- binding protein transpeptidase; KEGG: rce:RC1_2700 penicillin-binding protein, 1A family.
     
 0.435
Amir_6853
Inositol 2-dehydrogenase; PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: bbt:BBta_0488 inositol 2-dehydrogenase.
 
    0.414
Your Current Organism:
Actinosynnema mirum
NCBI taxonomy Id: 446462
Other names: A. mirum DSM 43827, Actinosynnema mirum DSM 43827, Actinosynnema mirum str. DSM 43827, Actinosynnema mirum strain DSM 43827
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