close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Amir_5259Transcriptional regulator, GntR family; PFAM: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: bha:BH0419 GntR family transcriptional regulator. (254 aa)    
Predicted Functional Partners:
Amir_5260
PFAM: phosphotransferase system EIIC; KEGG: bha:BH0422 PTS system, N-acetylglucosamine- specific enzyme II, ABC component.
 
   
 0.847
Amir_5605
Transcriptional regulator, GntR family; PFAM: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: sil:SPO0467 GntR family transcriptional regulator.
  
     0.761
Amir_1284
Transcriptional regulator, GntR family; PFAM: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: dar:Daro_2866 GntR family transcriptional regulator.
  
     0.754
Amir_5261
Phosphotransferase system, phosphocarrier protein HPr; TIGRFAM: phosphocarrier, HPr family; PFAM: phosphoryl transfer system HPr; KEGG: aeh:Mlg_2234 HPr family phosphocarrier protein.
     
 0.726
Amir_5257
TIGRFAM: PTS system, glucose subfamily, IIA subunit; PFAM: sugar-specific permease EIIA 1 domain; KEGG: bsu:BSU39270 phosphotransferase system (PTS) beta-glucoside-specific enzyme IIBCA component.
 
   
 0.668
Amir_5258
PFAM: phosphotransferase system PTS EIIB protein; KEGG: esa:ESA_00528 hypothetical protein.
 
  
 0.663
Amir_6358
Transcriptional regulator, GntR family; PFAM: regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: met:M446_0773 GntR family transcriptional regulator.
  
     0.654
Amir_6924
KEGG: smt:Smal_3421 N-acetylglucosamine-6-phosphate deacetylase; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase; PFAM: amidohydrolase.
 
  
 0.445
Amir_4755
Putative transcriptional regulator; KEGG: ank:AnaeK_1843 SpoIID/LytB domain protein.
   
  
 0.422
Amir_4422
Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: reh:H16_B0937 transcriptional regulator, AraC- family.
  
  
 0.411
Your Current Organism:
Actinosynnema mirum
NCBI taxonomy Id: 446462
Other names: A. mirum DSM 43827, Actinosynnema mirum DSM 43827, Actinosynnema mirum str. DSM 43827, Actinosynnema mirum strain DSM 43827
Server load: low (24%) [HD]