STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Amir_5273KEGG: hypothetical protein; K00876 uridine kinase. (212 aa)    
Predicted Functional Partners:
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
  
 0.980
Amir_0143
PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; KEGG: scl:sce7039 putative 5'-nucleotidase family protein; Belongs to the 5'-nucleotidase family.
 
 
 0.924
cmk
KEGG: gur:Gura_1465 cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region.
   
 
 0.919
pyrH
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
   
 
 0.919
Amir_4885
PFAM: purine or other phosphorylase family 1; KEGG: aha:AHA_3168 uridine phosphorylase.
    
 0.916
pyrF
TIGRFAM: orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase; KEGG: mxa:MXAN_5910 orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily.
  
 0.913
pyrR
Uracil phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
     
 0.911
Amir_6450
PFAM: CMP/dCMP deaminase zinc-binding; KEGG: nar:Saro_0145 cytidine deaminase.
    
 0.910
Amir_4943
PFAM: Survival protein SurE; KEGG: rce:RC1_0808 5'/3'-nucleotidase SurE.
     
 0.905
Amir_5199
KEGG: bha:BH3560 glyceraldehyde-3-phosphate dehydrogenase; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
   
 
 0.721
Your Current Organism:
Actinosynnema mirum
NCBI taxonomy Id: 446462
Other names: A. mirum DSM 43827, Actinosynnema mirum DSM 43827, Actinosynnema mirum str. DSM 43827, Actinosynnema mirum strain DSM 43827
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