STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Amir_5670Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: pmy:Pmen_2972 AraC family transcriptional regulator. (335 aa)    
Predicted Functional Partners:
Amir_6777
PFAM: aminotransferase class I and II; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: mxa:MXAN_3751 aminotransferase, classes I and II.
      0.530
Amir_5669
PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; KEGG: pmy:Pmen_2590 short chain enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase.
  
     0.504
Amir_1314
PFAM: regulatory protein TetR; KEGG: mlo:mll3939 TetR family transcriptional regulator.
  
     0.457
Amir_4218
Transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate- binding; KEGG: aha:AHA_4117 regulatory protein, LysR:LysR, substrate-binding; Belongs to the LysR transcriptional regulatory family.
  
    0.448
Amir_3747
PFAM: FAD dependent oxidoreductase; KEGG: bur:Bcep18194_B2514 lipolytic protein.
  
     0.425
Amir_4466
PFAM: regulatory protein TetR; KEGG: pla:Plav_1079 TetR family transcriptional regulator.
  
     0.410
Amir_2638
PFAM: FAD dependent oxidoreductase; KEGG: scl:sce3282 monooxygenase flavin-binding family protein.
 
   
 0.405
Your Current Organism:
Actinosynnema mirum
NCBI taxonomy Id: 446462
Other names: A. mirum DSM 43827, Actinosynnema mirum DSM 43827, Actinosynnema mirum str. DSM 43827, Actinosynnema mirum strain DSM 43827
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.