STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Amir_5726PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: eta:ETA_23610 putative hydrolase. (259 aa)    
Predicted Functional Partners:
egtE
Aminotransferase class V; Probably catalyzes the conversion of hercynylcysteine sulfoxide to ergothioneine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. EgtE subfamily.
       0.569
Amir_5725
PFAM: extracellular solute-binding protein family 5; KEGG: ses:SARI_01727 hypothetical protein.
       0.569
Amir_0791
PFAM: major facilitator superfamily MFS_1; KEGG: acr:Acry_1491 major facilitator transporter.
 
      0.479
Amir_5727
PFAM: PRC-barrel domain protein; KEGG: atc:AGR_C_723 hypothetical protein.
       0.474
Amir_3294
PFAM: Acyl transferase; AMP-dependent synthetase and ligase; Beta-ketoacyl synthase; Alcohol dehydrogenase GroES domain protein; short-chain dehydrogenase/reductase SDR; KR domain protein; Alcohol dehydrogenase zinc-binding domain protein; NAD-dependent epimerase/dehydratase; phosphopantetheine-binding; KEGG: pst:PSPTO_4686 coronafacic acid polyketide synthase I.
   
 
 0.426
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
   
 
 0.417
Your Current Organism:
Actinosynnema mirum
NCBI taxonomy Id: 446462
Other names: A. mirum DSM 43827, Actinosynnema mirum DSM 43827, Actinosynnema mirum str. DSM 43827, Actinosynnema mirum strain DSM 43827
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