STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Amir_6333TIGRFAM: LPPG domain protein containing protein; PFAM: protein of unknown function UPF0052 and CofD; KEGG: rpb:RPB_4407 LPPG:FO 2-phospho-L-lactate transferase. (321 aa)    
Predicted Functional Partners:
Amir_6334
TIGRFAM: F420-dependent oxidoreductase; PFAM: protein of unknown function DUF129; nitroreductase; KEGG: pde:Pden_1118 F420-dependent oxidoreductase, putative.
 
 
 0.999
fbiD
Conserved hypothetical protein; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.
 
  
 0.994
whiA
Protein of unknown function DUF199; Involved in cell division and chromosome segregation.
  
  
 0.894
Amir_6472
PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: swi:Swit_0717 FO synthase.
 
   
 0.889
Amir_6335
PFAM: NUDIX hydrolase; KEGG: sml:Smlt2194 hypothetical protein.
  
    0.831
Amir_4989
Hypothetical protein.
  
   
 0.785
Amir_5205
Conserved hypothetical protein; Displays ATPase and GTPase activities.
  
  
 0.783
Amir_4020
PFAM: Luciferase-like monooxygenase; KEGG: oca:OCAR_4999 hypothetical protein.
 
   
 0.771
Amir_3523
PFAM: Luciferase-like monooxygenase; KEGG: pzu:PHZ_c2543 5,10- methylenetetrahydromethanopterin reductase.
 
   
 0.765
Amir_2715
PFAM: Luciferase-like monooxygenase; KEGG: rpb:RPB_4431 coenzyme F420-dependent N(5),N(10)-methenyltetrahydromethanopterin.
 
   
 0.755
Your Current Organism:
Actinosynnema mirum
NCBI taxonomy Id: 446462
Other names: A. mirum DSM 43827, Actinosynnema mirum DSM 43827, Actinosynnema mirum str. DSM 43827, Actinosynnema mirum strain DSM 43827
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