STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Amir_6449KEGG: mxa:MXAN_5710 pyrimidine-nucleoside phosphorylase; TIGRFAM: pyrimidine-nucleoside phosphorylase; PFAM: glycosyl transferase family 3; Pyrimidine nucleoside phosphorylase domain; Glycosyl transferase, family 3-like. (424 aa)    
Predicted Functional Partners:
Amir_6450
PFAM: CMP/dCMP deaminase zinc-binding; KEGG: nar:Saro_0145 cytidine deaminase.
 
 0.998
Amir_6421
Purine nucleotide phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
 
  
 0.968
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
 
 
 0.959
Amir_4885
PFAM: purine or other phosphorylase family 1; KEGG: aha:AHA_3168 uridine phosphorylase.
  
 
 0.951
Amir_3408
PFAM: thymidine kinase; KEGG: aha:AHA_1822 thymidine kinase.
 
  
 0.930
deoC
Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
 
 
 0.924
Amir_4943
PFAM: Survival protein SurE; KEGG: rce:RC1_0808 5'/3'-nucleotidase SurE.
    
 0.915
pyrR
Uracil phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
     
 0.912
Amir_0143
PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; KEGG: scl:sce7039 putative 5'-nucleotidase family protein; Belongs to the 5'-nucleotidase family.
    
 0.909
Amir_0538
PFAM: Amidohydrolase 3; KEGG: bac:BamMC406_5450 N-isopropylammelide isopropylaminohydrolase.
    
 0.906
Your Current Organism:
Actinosynnema mirum
NCBI taxonomy Id: 446462
Other names: A. mirum DSM 43827, Actinosynnema mirum DSM 43827, Actinosynnema mirum str. DSM 43827, Actinosynnema mirum strain DSM 43827
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.