node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Amir_0558 | Amir_7013 | Amir_0558 | Amir_7013 | Molecular chaperone-like protein; KEGG: hha:Hhal_0145 heat shock protein 70. | KEGG: hypothetical protein; Belongs to the small heat shock protein (HSP20) family. | 0.545 |
Amir_0558 | clpB | Amir_0558 | Amir_6943 | Molecular chaperone-like protein; KEGG: hha:Hhal_0145 heat shock protein 70. | ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.769 |
Amir_0558 | clpP | Amir_0558 | Amir_1098 | Molecular chaperone-like protein; KEGG: hha:Hhal_0145 heat shock protein 70. | Endopeptidase Clp; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.625 |
Amir_0558 | clpP-2 | Amir_0558 | Amir_1099 | Molecular chaperone-like protein; KEGG: hha:Hhal_0145 heat shock protein 70. | Endopeptidase Clp; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.543 |
Amir_0558 | clpP-3 | Amir_0558 | Amir_1153 | Molecular chaperone-like protein; KEGG: hha:Hhal_0145 heat shock protein 70. | Endopeptidase Clp; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.543 |
Amir_0558 | dnaJ-2 | Amir_0558 | Amir_6947 | Molecular chaperone-like protein; KEGG: hha:Hhal_0145 heat shock protein 70. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.840 |
Amir_0558 | dnaK | Amir_0558 | Amir_6949 | Molecular chaperone-like protein; KEGG: hha:Hhal_0145 heat shock protein 70. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.429 |
Amir_0558 | grpE | Amir_0558 | Amir_6948 | Molecular chaperone-like protein; KEGG: hha:Hhal_0145 heat shock protein 70. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.944 |
Amir_1415 | Amir_7013 | Amir_1415 | Amir_7013 | PFAM: Heat shock protein 70; KEGG: hha:Hhal_0145 heat shock protein 70. | KEGG: hypothetical protein; Belongs to the small heat shock protein (HSP20) family. | 0.545 |
Amir_1415 | clpB | Amir_1415 | Amir_6943 | PFAM: Heat shock protein 70; KEGG: hha:Hhal_0145 heat shock protein 70. | ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.769 |
Amir_1415 | clpP | Amir_1415 | Amir_1098 | PFAM: Heat shock protein 70; KEGG: hha:Hhal_0145 heat shock protein 70. | Endopeptidase Clp; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.625 |
Amir_1415 | clpP-2 | Amir_1415 | Amir_1099 | PFAM: Heat shock protein 70; KEGG: hha:Hhal_0145 heat shock protein 70. | Endopeptidase Clp; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.543 |
Amir_1415 | clpP-3 | Amir_1415 | Amir_1153 | PFAM: Heat shock protein 70; KEGG: hha:Hhal_0145 heat shock protein 70. | Endopeptidase Clp; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.543 |
Amir_1415 | dnaJ-2 | Amir_1415 | Amir_6947 | PFAM: Heat shock protein 70; KEGG: hha:Hhal_0145 heat shock protein 70. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.918 |
Amir_1415 | grpE | Amir_1415 | Amir_6948 | PFAM: Heat shock protein 70; KEGG: hha:Hhal_0145 heat shock protein 70. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.951 |
Amir_6569 | Amir_7013 | Amir_6569 | Amir_7013 | PFAM: Heat shock protein 70; KEGG: mag:amb3024 chaperone protein HscA. | KEGG: hypothetical protein; Belongs to the small heat shock protein (HSP20) family. | 0.545 |
Amir_6569 | clpB | Amir_6569 | Amir_6943 | PFAM: Heat shock protein 70; KEGG: mag:amb3024 chaperone protein HscA. | ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.769 |
Amir_6569 | clpP | Amir_6569 | Amir_1098 | PFAM: Heat shock protein 70; KEGG: mag:amb3024 chaperone protein HscA. | Endopeptidase Clp; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.625 |
Amir_6569 | clpP-2 | Amir_6569 | Amir_1099 | PFAM: Heat shock protein 70; KEGG: mag:amb3024 chaperone protein HscA. | Endopeptidase Clp; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.543 |
Amir_6569 | clpP-3 | Amir_6569 | Amir_1153 | PFAM: Heat shock protein 70; KEGG: mag:amb3024 chaperone protein HscA. | Endopeptidase Clp; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.543 |