STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Amir_7009Two component transcriptional regulator, LuxR family; PFAM: response regulator receiver; regulatory protein LuxR; Sigma-70 region 4 type 2; sigma-70 region 4 domain protein; SMART: response regulator receiver; regulatory protein LuxR; KEGG: scl:sce5431 two-component system response regulator. (218 aa)    
Predicted Functional Partners:
Amir_7008
PFAM: histidine kinase dimerization and phosphoacceptor region; ATP-binding region ATPase domain protein; KEGG: scl:sce5432 putative two-component system sensor kinase.
   0.917
Amir_2370
KEGG: dal:Dalk_3918 multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; Hpt domain protein; PAS fold- 4 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS domain containing protein.
   
 
 0.843
Amir_4052
PFAM: histidine kinase dimerization and phosphoacceptor region; ATP-binding region ATPase domain protein; KEGG: mmr:Mmar10_2544 putative signal transduction histidine kinase.
 
   0.784
Amir_2233
PFAM: histidine kinase dimerization and phosphoacceptor region; ATP-binding region ATPase domain protein; KEGG: scl:sce5432 putative two-component system sensor kinase.
 
   0.778
Amir_1618
PFAM: histidine kinase dimerization and phosphoacceptor region; ATP-binding region ATPase domain protein; KEGG: scl:sce5432 putative two-component system sensor kinase.
  
   0.761
Amir_7014
Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerization and phosphoacceptor region; SMART: ATP-binding region ATPase domain protein; KEGG: scl:sce5432 putative two-component system sensor kinase.
  
   0.754
Amir_6236
PFAM: histidine kinase dimerization and phosphoacceptor region; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; KEGG: scl:sce5432 putative two-component system sensor kinase.
  
   0.746
Amir_2009
PFAM: histidine kinase dimerization and phosphoacceptor region; ATP-binding region ATPase domain protein; KEGG: scl:sce5432 putative two-component system sensor kinase.
  
   0.739
Amir_0512
PFAM: histidine kinase dimerization and phosphoacceptor region; ATP-binding region ATPase domain protein; KEGG: sus:Acid_1273 integral membrane sensor signal transduction histidine kinase.
 
   0.738
Amir_2410
PFAM: histidine kinase dimerization and phosphoacceptor region; ATP-binding region ATPase domain protein; KEGG: scl:sce5432 putative two-component system sensor kinase.
 
   0.733
Your Current Organism:
Actinosynnema mirum
NCBI taxonomy Id: 446462
Other names: A. mirum DSM 43827, Actinosynnema mirum DSM 43827, Actinosynnema mirum str. DSM 43827, Actinosynnema mirum strain DSM 43827
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.