STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACU84087.1Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (184 aa)    
Predicted Functional Partners:
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
 
 0.816
rplB
LSU ribosomal protein L2P; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
   
 
 0.793
ACU84086.1
Hypothetical protein.
  
 
 0.789
ACU84240.1
ATP-dependent helicase HrpB; PFAM: Helicase conserved C-terminal domain; Helicase associated domain (HA2); ATP-dependent helicase C-terminal; TIGRFAM: ATP-dependent helicase HrpB.
   
 0.764
ACU85831.1
ATP-dependent helicase HrpA; PFAM: Domain of unknown function (DUF1605); Helicase associated domain (HA2); Helicase conserved C-terminal domain; TIGRFAM: ATP-dependent helicase HrpA.
   
 0.764
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
  
 0.758
ACU84612.1
Hypothetical protein.
   
 0.756
fusA
Translation elongation factor 2 (EF-2/EF-G); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. [...]
   
 0.750
ACU84978.1
DNA/RNA helicase, superfamily II; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase; Belongs to the DEAD box helicase family.
 
 0.743
rplN
LSU ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
   
   0.734
Your Current Organism:
Brachybacterium faecium
NCBI taxonomy Id: 446465
Other names: B. faecium DSM 4810, Brachybacterium faecium ATCC 43885, Brachybacterium faecium DSM 4810, Brachybacterium faecium str. DSM 4810, Brachybacterium faecium strain DSM 4810
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.