Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACU84564.1Phosphotransferase system, mannitol-specific IIBC component; PFAM: PTS system, Lactose/Cellobiose specific IIB subunit; Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; Phosphotransferase system, EIIC; TIGRFAM: PTS system, mannitol-specific IIC component. (687 aa)    
Predicted Functional Partners:
mtlD
D-mannitol 1-phosphate 5-dehydrogenase; PFAM: Mannitol dehydrogenase C-terminal domain; Mannitol dehydrogenase Rossmann domain.
 
 
 0.999
ACU86032.1
PFAM: Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; Phosphotransferase system, EIIC; PTS system, Fructose specific IIB subunit; TIGRFAM: PTS system, fructose subfamily, IIC component; PTS system, fructose subfamily, IIA component; PTS system, fructose-specific, IIB component.
 
  
 0.998
ACU84562.1
PFAM: PTS HPr component phosphorylation site; TIGRFAM: Phosphotransferase System HPr (HPr) Family.
 
 
 0.995
ACU86864.1
PFAM: Mannitol dehydrogenase C-terminal domain; Mannitol dehydrogenase Rossmann domain.
 
  
 0.988
ACU84227.1
PFAM: PTS HPr component phosphorylation site; TIGRFAM: Phosphotransferase System HPr (HPr) Family.
   
 0.987
ACU86031.1
1-phosphofructokinase; PFAM: pfkB family carbohydrate kinase; TIGRFAM: 1-phosphofructokinase.
 
  
 0.962
ACU84892.1
PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED.
    
 0.905
ACU84257.1
PFAM: Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2.
 
  
 0.900
ACU84561.1
Phosphoenolpyruvate--protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
   
 0.860
ACU85439.1
tRNA/rRNA cytosine-C5-methylase; PFAM: NusB family; NOL1/NOP2/sun family; TIGRFAM: ribosomal RNA small subunit methyltransferase RsmB; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
      
 0.614
Your Current Organism:
Brachybacterium faecium
NCBI taxonomy Id: 446465
Other names: B. faecium DSM 4810, Brachybacterium faecium ATCC 43885, Brachybacterium faecium DSM 4810, Brachybacterium faecium str. DSM 4810, Brachybacterium faecium strain DSM 4810
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