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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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textmining
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
ACU84662.1PFAM: Phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase. (291 aa)    
Predicted Functional Partners:
thiE
Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
 
 0.998
ACU86503.1
PFAM: TENA/THI-4/PQQC family; Phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase.
 
 
0.972
thiM
Hydroxyethylthiazole kinase, sugar kinase family; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family.
  
 0.929
thiG
Thiazole-phosphate synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
 
  
 0.792
ACU84054.1
PFAM: ThiS family; TIGRFAM: thiamine biosynthesis protein ThiS.
  
  
 0.675
ACU84708.1
Dinucleotide-utilizing enzyme possibly involved in molybdopterin or thiamin biosynthesis; PFAM: ThiF family; MoeZ/MoeB domain.
 
  
 0.603
ACU84052.1
Dinucleotide-utilizing enzyme possibly involved in molybdopterin or thiamin biosynthesis; PFAM: ThiF family; Rhodanese-like domain; MoeZ/MoeB domain.
 
  
 0.599
ACU84661.1
Hypothetical protein.
       0.511
ACU84632.1
DNA/RNA helicase, superfamily II; PFAM: DEAD/DEAH box helicase; Helicase conserved C-terminal domain.
 
 
    0.433
ACU84660.1
Hypothetical protein.
       0.416
Your Current Organism:
Brachybacterium faecium
NCBI taxonomy Id: 446465
Other names: B. faecium DSM 4810, Brachybacterium faecium ATCC 43885, Brachybacterium faecium DSM 4810, Brachybacterium faecium str. DSM 4810, Brachybacterium faecium strain DSM 4810
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