node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACU84777.1 | ACU84779.1 | Bfae_09240 | Bfae_09260 | 4-diphosphocytidyl-2-methyl-D-erythritol synthase; PFAM: Uncharacterized protein family UPF0007; TIGRFAM: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily. | 4-diphosphocytidyl-2-methyl-D-erythritol synthase; PFAM: Uncharacterized protein family UPF0007. | 0.900 |
ACU84777.1 | ACU85286.1 | Bfae_09240 | Bfae_14550 | 4-diphosphocytidyl-2-methyl-D-erythritol synthase; PFAM: Uncharacterized protein family UPF0007; TIGRFAM: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily. | Deoxyxylulose-5-phosphate synthase; PFAM: Transketolase, pyrimidine binding domain; Transketolase, C-terminal domain; TIGRFAM: 1-deoxy-D-xylulose-5-phosphate synthase. | 0.743 |
ACU84777.1 | ACU86415.1 | Bfae_09240 | Bfae_26410 | 4-diphosphocytidyl-2-methyl-D-erythritol synthase; PFAM: Uncharacterized protein family UPF0007; TIGRFAM: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily. | 4-diphosphocytidyl-2-methyl-D-erythritol synthase; PFAM: Uncharacterized protein family UPF0007; TIGRFAM: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase. | 0.926 |
ACU84777.1 | dxr | Bfae_09240 | Bfae_10200 | 4-diphosphocytidyl-2-methyl-D-erythritol synthase; PFAM: Uncharacterized protein family UPF0007; TIGRFAM: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily. | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 0.981 |
ACU84777.1 | ispE | Bfae_09240 | Bfae_13310 | 4-diphosphocytidyl-2-methyl-D-erythritol synthase; PFAM: Uncharacterized protein family UPF0007; TIGRFAM: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily. | 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | 0.977 |
ACU84777.1 | ispF | Bfae_09240 | Bfae_09220 | 4-diphosphocytidyl-2-methyl-D-erythritol synthase; PFAM: Uncharacterized protein family UPF0007; TIGRFAM: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily. | 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). | 0.996 |
ACU84777.1 | ispG | Bfae_09240 | Bfae_10220 | 4-diphosphocytidyl-2-methyl-D-erythritol synthase; PFAM: Uncharacterized protein family UPF0007; TIGRFAM: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily. | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. | 0.785 |
ACU84777.1 | ispH | Bfae_09240 | Bfae_22960 | 4-diphosphocytidyl-2-methyl-D-erythritol synthase; PFAM: Uncharacterized protein family UPF0007; TIGRFAM: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily. | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.763 |
ACU84779.1 | ACU84777.1 | Bfae_09260 | Bfae_09240 | 4-diphosphocytidyl-2-methyl-D-erythritol synthase; PFAM: Uncharacterized protein family UPF0007. | 4-diphosphocytidyl-2-methyl-D-erythritol synthase; PFAM: Uncharacterized protein family UPF0007; TIGRFAM: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily. | 0.900 |
ACU84779.1 | ACU85286.1 | Bfae_09260 | Bfae_14550 | 4-diphosphocytidyl-2-methyl-D-erythritol synthase; PFAM: Uncharacterized protein family UPF0007. | Deoxyxylulose-5-phosphate synthase; PFAM: Transketolase, pyrimidine binding domain; Transketolase, C-terminal domain; TIGRFAM: 1-deoxy-D-xylulose-5-phosphate synthase. | 0.785 |
ACU84779.1 | ACU86415.1 | Bfae_09260 | Bfae_26410 | 4-diphosphocytidyl-2-methyl-D-erythritol synthase; PFAM: Uncharacterized protein family UPF0007. | 4-diphosphocytidyl-2-methyl-D-erythritol synthase; PFAM: Uncharacterized protein family UPF0007; TIGRFAM: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase. | 0.900 |
ACU84779.1 | dxr | Bfae_09260 | Bfae_10200 | 4-diphosphocytidyl-2-methyl-D-erythritol synthase; PFAM: Uncharacterized protein family UPF0007. | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 0.977 |
ACU84779.1 | ispE | Bfae_09260 | Bfae_13310 | 4-diphosphocytidyl-2-methyl-D-erythritol synthase; PFAM: Uncharacterized protein family UPF0007. | 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | 0.977 |
ACU84779.1 | ispF | Bfae_09260 | Bfae_09220 | 4-diphosphocytidyl-2-methyl-D-erythritol synthase; PFAM: Uncharacterized protein family UPF0007. | 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). | 0.922 |
ACU84779.1 | ispG | Bfae_09260 | Bfae_10220 | 4-diphosphocytidyl-2-methyl-D-erythritol synthase; PFAM: Uncharacterized protein family UPF0007. | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. | 0.780 |
ACU84779.1 | ispH | Bfae_09260 | Bfae_22960 | 4-diphosphocytidyl-2-methyl-D-erythritol synthase; PFAM: Uncharacterized protein family UPF0007. | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.780 |
ACU84871.1 | dxr | Bfae_10230 | Bfae_10200 | Predicted acyltransferase; PFAM: Acetyltransferase (GNAT) family. | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 0.610 |
ACU84871.1 | ispG | Bfae_10230 | Bfae_10220 | Predicted acyltransferase; PFAM: Acetyltransferase (GNAT) family. | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. | 0.841 |
ACU85286.1 | ACU84777.1 | Bfae_14550 | Bfae_09240 | Deoxyxylulose-5-phosphate synthase; PFAM: Transketolase, pyrimidine binding domain; Transketolase, C-terminal domain; TIGRFAM: 1-deoxy-D-xylulose-5-phosphate synthase. | 4-diphosphocytidyl-2-methyl-D-erythritol synthase; PFAM: Uncharacterized protein family UPF0007; TIGRFAM: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily. | 0.743 |
ACU85286.1 | ACU84779.1 | Bfae_14550 | Bfae_09260 | Deoxyxylulose-5-phosphate synthase; PFAM: Transketolase, pyrimidine binding domain; Transketolase, C-terminal domain; TIGRFAM: 1-deoxy-D-xylulose-5-phosphate synthase. | 4-diphosphocytidyl-2-methyl-D-erythritol synthase; PFAM: Uncharacterized protein family UPF0007. | 0.785 |