STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cmkCytidylate kinase; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the cytidylate kinase family. Type 1 subfamily. (755 aa)    
Predicted Functional Partners:
ACU85360.1
PFAM: S4 domain; RNA pseudouridylate synthase; TIGRFAM: pseudouridine synthase family; Belongs to the pseudouridine synthase RsuA family.
 
  
 0.996
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
  
  
 0.929
ffh
Signal recognition particle subunit FFH/SRP54 (srp54); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.
 
  
 0.911
nusA
Transcription termination factor NusA; Participates in both transcription termination and antitermination.
  
    0.907
ACU86213.1
Hypothetical protein.
  
    0.907
pheT
phenylalanyl-tRNA synthetase beta subunit; PFAM: B3/4 domain; Ferredoxin-fold anticodon binding domain; Putative tRNA binding domain; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit, non-spirochete bacterial; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
 
  
 0.906
gpsA-2
Glycerol-3-phosphate dehydrogenase; PFAM: NADP oxidoreductase coenzyme F420-dependent; NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
  
 0.898
ACU85361.1
PFAM: ACT domain; Prephenate dehydrogenase.
 
  
 0.894
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
  
 0.890
gpsA
PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; NADP oxidoreductase coenzyme F420-dependent; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
  
 0.889
Your Current Organism:
Brachybacterium faecium
NCBI taxonomy Id: 446465
Other names: B. faecium DSM 4810, Brachybacterium faecium ATCC 43885, Brachybacterium faecium DSM 4810, Brachybacterium faecium str. DSM 4810, Brachybacterium faecium strain DSM 4810
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