STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACU86873.1PFAM: Uncharacterized conserved protein (DUF2088). (453 aa)    
Predicted Functional Partners:
ACU86872.1
PFAM: PP-loop family; TIGRFAM: conserved hypothetical protein TIGR00268.
 
  
 0.979
ACU86871.1
NCAIR mutase-like protein; PFAM: AIR carboxylase.
 
  
 0.978
dld
D-lactate dehydrogenase; Catalyzes the oxidation of D-lactate to pyruvate. Belongs to the quinone-dependent D-lactate dehydrogenase family.
    
 0.906
ACU85044.1
Alpha-hydroxyacid dehydrogenase, FMN-dependent L-lactate dehydrogenase; PFAM: FMN-dependent dehydrogenase.
    
 0.902
ACU86579.1
Zn-dependent hydrolase, glyoxylase; PFAM: Metallo-beta-lactamase superfamily.
     
  0.900
larC
Conserved hypothetical protein TIGR00299; Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes. Belongs to the LarC family.
 
  
 0.833
ACU86874.1
Methyltransferase family protein; PFAM: Methyltransferase domain.
       0.491
ACU86485.1
HAD-superfamily subfamily IB hydrolase, TIGR01490; PFAM: Male sterility protein; TIGRFAM: Haloacid Dehalogenase superfamily, subfamily IB, phosphoserine phosphatase-like; HAD-superfamily subfamily IB hydrolase, TIGR01490.
 
     0.475
ACU83901.1
Hypothetical protein.
  
     0.459
ACU84576.1
Hypothetical protein.
 
     0.448
Your Current Organism:
Brachybacterium faecium
NCBI taxonomy Id: 446465
Other names: B. faecium DSM 4810, Brachybacterium faecium ATCC 43885, Brachybacterium faecium DSM 4810, Brachybacterium faecium str. DSM 4810, Brachybacterium faecium strain DSM 4810
Server load: medium (76%) [HD]