node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Cfla_0002 | Cfla_0005 | Cfla_0002 | Cfla_0005 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | PFAM: protein of unknown function DUF721; KEGG: protein of unknown function DUF721. | 0.801 |
Cfla_0002 | Cfla_0008 | Cfla_0002 | Cfla_0008 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | KEGG: bcv:Bcav_0008 hypothetical protein. | 0.693 |
Cfla_0002 | Cfla_1317 | Cfla_0002 | Cfla_1317 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | KEGG: mlu:Mlut_08270 hypothetical protein. | 0.480 |
Cfla_0002 | Cfla_1693 | Cfla_0002 | Cfla_1693 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | PFAM: DNA gyrase/topoisomerase IV subunit A; DNA gyrase repeat beta-propeller; KEGG: DNA topoisomerase (ATP-hydrolyzing); SMART: DNA gyrase/topoisomerase IV subunit A. | 0.485 |
Cfla_0002 | Cfla_2146 | Cfla_0002 | Cfla_2146 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | KEGG: hypothetical protein. | 0.493 |
Cfla_0002 | Cfla_2464 | Cfla_0002 | Cfla_2464 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | KEGG: bcv:Bcav_2890 hypothetical protein; TIGRFAM: conserved hypothetical protein; PFAM: Protein of unknown function DUF2342. | 0.434 |
Cfla_0002 | gyrA | Cfla_0002 | Cfla_0007 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.719 |
Cfla_0002 | gyrB | Cfla_0002 | Cfla_0006 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.799 |
Cfla_0005 | Cfla_0002 | Cfla_0005 | Cfla_0002 | PFAM: protein of unknown function DUF721; KEGG: protein of unknown function DUF721. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.801 |
Cfla_0005 | Cfla_0008 | Cfla_0005 | Cfla_0008 | PFAM: protein of unknown function DUF721; KEGG: protein of unknown function DUF721. | KEGG: bcv:Bcav_0008 hypothetical protein. | 0.760 |
Cfla_0005 | Cfla_0910 | Cfla_0005 | Cfla_0910 | PFAM: protein of unknown function DUF721; KEGG: protein of unknown function DUF721. | PFAM: Septum formation initiator; KEGG: bcv:Bcav_1019 septum formation initiator. | 0.402 |
Cfla_0005 | Cfla_2146 | Cfla_0005 | Cfla_2146 | PFAM: protein of unknown function DUF721; KEGG: protein of unknown function DUF721. | KEGG: hypothetical protein. | 0.600 |
Cfla_0005 | Cfla_2464 | Cfla_0005 | Cfla_2464 | PFAM: protein of unknown function DUF721; KEGG: protein of unknown function DUF721. | KEGG: bcv:Bcav_2890 hypothetical protein; TIGRFAM: conserved hypothetical protein; PFAM: Protein of unknown function DUF2342. | 0.460 |
Cfla_0005 | gyrA | Cfla_0005 | Cfla_0007 | PFAM: protein of unknown function DUF721; KEGG: protein of unknown function DUF721. | DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.528 |
Cfla_0005 | gyrB | Cfla_0005 | Cfla_0006 | PFAM: protein of unknown function DUF721; KEGG: protein of unknown function DUF721. | DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.673 |
Cfla_0005 | whiB-2 | Cfla_0005 | Cfla_2396 | PFAM: protein of unknown function DUF721; KEGG: protein of unknown function DUF721. | Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA. | 0.471 |
Cfla_0008 | Cfla_0002 | Cfla_0008 | Cfla_0002 | KEGG: bcv:Bcav_0008 hypothetical protein. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.693 |
Cfla_0008 | Cfla_0005 | Cfla_0008 | Cfla_0005 | KEGG: bcv:Bcav_0008 hypothetical protein. | PFAM: protein of unknown function DUF721; KEGG: protein of unknown function DUF721. | 0.760 |
Cfla_0008 | Cfla_0910 | Cfla_0008 | Cfla_0910 | KEGG: bcv:Bcav_0008 hypothetical protein. | PFAM: Septum formation initiator; KEGG: bcv:Bcav_1019 septum formation initiator. | 0.695 |
Cfla_0008 | Cfla_1317 | Cfla_0008 | Cfla_1317 | KEGG: bcv:Bcav_0008 hypothetical protein. | KEGG: mlu:Mlut_08270 hypothetical protein. | 0.668 |