STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cfla_0073KEGG: tfu:Tfu_1377 isocitrate lyase; TIGRFAM: isocitrate lyase; PFAM: isocitrate lyase and phosphorylmutase. (452 aa)    
Predicted Functional Partners:
Cfla_0074
TIGRFAM: malate synthase A; KEGG: aau:AAur_0721 malate synthase; PFAM: Malate synthase family protein; Belongs to the malate synthase family.
 
 0.999
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
   
  
 0.946
Cfla_1712
Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
   
 
 0.923
Cfla_3011
KEGG: kra:Krad_0201 2-dehydro-3- deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; TIGRFAM: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; PFAM: KDPG and KHG aldolase.
     
 0.905
Cfla_2577
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
   
  
 0.835
Cfla_0995
TIGRFAM: citrate synthase I; KEGG: jde:Jden_0803 citrate synthase I; PFAM: Citrate synthase; Belongs to the citrate synthase family.
   
  
 0.725
Cfla_0072
KEGG: transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; protein of unknown function DUF955; SMART: helix-turn-helix domain protein.
 
   
 0.708
Cfla_1724
PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; 3-hydroxyacyl-CoA dehydrogenase domain protein; Enoyl-CoA hydratase/isomerase; KEGG: bcv:Bcav_1960 3-hydroxyacyl-CoA dehydrogenase NAD-binding.
  
  
 0.658
pckG
Phosphoenolpyruvate carboxykinase (GTP); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
      
 0.552
Cfla_1219
KEGG: 2-oxoglutarate dehydrogenase, E1 subunit; TIGRFAM: 2-oxoglutarate dehydrogenase, E1 subunit; PFAM: Transketolase central region; dehydrogenase E1 component; catalytic domain of components of various dehydrogenase complexes.
   
  
 0.548
Your Current Organism:
Cellulomonas flavigena
NCBI taxonomy Id: 446466
Other names: C. flavigena DSM 20109, Cellulomonas flavigena DSM 20109, Cellulomonas flavigena str. DSM 20109, Cellulomonas flavigena strain DSM 20109
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