STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
panDAspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (155 aa)    
Predicted Functional Partners:
panC
Pantoate/beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
 
 
 0.999
Cfla_0637
L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
    
 0.945
panB
3-methyl-2-oxobutanoatehydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
 
  
 0.941
Cfla_1438
PFAM: aminotransferase class-III; KEGG: aau:AAur_1939 hypothetical protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
     
 0.913
Cfla_1431
PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: bcv:Bcav_2579 nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase.
    
  0.902
Cfla_0634
PFAM: Putative oxidoreductase/dehydrogenase, Rossmann-like domain; Domain of unknown function DUF2520; KEGG: bcv:Bcav_0716 pantoate/beta-alanine ligase.
 
     0.864
Cfla_0429
PFAM: Ketopantoate hydroxymethyltransferase; KEGG: svi:Svir_07360 ketopantoate hydroxymethyltransferase.
  
  
 0.836
Cfla_0633
PFAM: membrane-flanked domain; KEGG: membrane-flanked domain protein.
       0.835
Cfla_0632
PFAM: membrane-flanked domain; KEGG: bcv:Bcav_0707 membrane-flanked domain protein.
       0.834
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
    
  0.810
Your Current Organism:
Cellulomonas flavigena
NCBI taxonomy Id: 446466
Other names: C. flavigena DSM 20109, Cellulomonas flavigena DSM 20109, Cellulomonas flavigena str. DSM 20109, Cellulomonas flavigena strain DSM 20109
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.