STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cfla_2136KEGG: art:Arth_4243 hypothetical protein. (281 aa)    
Predicted Functional Partners:
Cfla_2135
KEGG: art:Arth_4242 hypothetical protein.
       0.799
Cfla_0002
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.721
Cfla_0379
Transcriptional regulator, MerR family; KEGG: sco:SCO1180 DNA polymerase III beta chain; PFAM: regulatory protein MerR; DNA polymerase III beta chain; SMART: regulatory protein MerR.
   
 0.721
Cfla_1901
PHP domain protein; KEGG: sgr:SGR_483 hypothetical protein; PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein.
  
 0.712
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.600
Cfla_3602
KEGG: scl:sce3748 sugar phosphatase; TIGRFAM: hydrolase, HAD-superfamily, subfamily IIIA; histidinol-phosphate phosphatase family protein; PFAM: Haloacid dehalogenase domain protein hydrolase.
   
 0.451
Cfla_2133
KEGG: ami:Amir_4351 two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver.
       0.445
Cfla_2134
Integral membrane sensor signal transduction histidine kinase; KEGG: ami:Amir_4352 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein.
       0.445
Cfla_0549
KEGG: bcv:Bcav_3648 exodeoxyribonuclease III Xth; TIGRFAM: exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase.
  
 
 0.442
Cfla_2498
KEGG: bcv:Bcav_2985 exodeoxyribonuclease III Xth; TIGRFAM: exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase.
  
 
 0.442
Your Current Organism:
Cellulomonas flavigena
NCBI taxonomy Id: 446466
Other names: C. flavigena DSM 20109, Cellulomonas flavigena DSM 20109, Cellulomonas flavigena str. DSM 20109, Cellulomonas flavigena strain DSM 20109
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