STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ndas_0784KEGG: tfu:Tfu_0919 hypothetical protein; SPTR: C1YN69 Putative uncharacterized protein. (93 aa)    
Predicted Functional Partners:
nnrD
Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...]
  
 0.881
Ndas_2726
Helicase domain protein; COGs: COG0553 Superfamily II DNA/RNA helicase SNF2 family; InterPro IPR001650:IPR014021:IPR014001:IPR000330; KEGG: tcu:Tcur_2545 helicase domain protein; PFAM: helicase domain protein; SNF2-related protein; SMART: helicase domain protein; DEAD-like helicase; SPTR: C1YKC4 DNA/RNA helicase, superfamily II, SNF2 family; PFAM: Helicase conserved C-terminal domain; SNF2 family N-terminal domain.
  
 0.618
Ndas_1264
DEAD/DEAH box helicase domain protein; COGs: COG0513 Superfamily II DNA and RNA helicase; InterProIPR014021:IPR001650:IPR014014:IPR014001:IPR 011545; KEGG: sma:SAV_4155 ATP-dependent RNA helicase; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: C1YU72 DNA/RNA helicase, superfamily II (Fragment); PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase.
   
 0.527
Ndas_2799
DEAD/DEAH box helicase domain protein; COGs: COG0513 Superfamily II DNA and RNA helicase; InterProIPR014001:IPR001650:IPR014021:IPR014014:IPR 011545; KEGG: sro:Sros_5980 DEAD/DEAH box helicase domain-containing protein; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: C1YK49 DNA/RNA helicase, superfamily II; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase.
   
 0.527
Ndas_3832
DEAD/DEAH box helicase domain protein; COGs: COG0513 Superfamily II DNA and RNA helicase; InterProIPR011545:IPR001650:IPR000629:IPR008162:IPR 014021:IPR014001; KEGG: tfu:Tfu_0514 helicase, C-terminal:DEAD/DEAH box helicase, N-terminal; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: C1YL18 DNA/RNA helicase, superfamily II; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase; Belongs to the DEAD box helicase family.
   
 0.527
Ndas_4476
DEAD/DEAH box helicase domain protein; COGs: COG0513 Superfamily II DNA and RNA helicase; InterProIPR014021:IPR001650:IPR014014:IPR011545:IPR 014001; KEGG: sma:SAV_4155 ATP-dependent RNA helicase; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: C1YG92 DNA/RNA helicase, superfamily II; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase.
   
 0.527
Ndas_0783
COGs: COG4339 conserved hypothetical protein; InterPro IPR009218; KEGG: tfu:Tfu_0918 hypothetical protein; SPTR: C1YN70 Uncharacterized conserved protein.
 
     0.517
rph
Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
    
 0.503
Ndas_2716
KEGG: bfa:Bfae_15660 hypothetical protein; SPTR: C1YKD5 Putative uncharacterized protein.
  
     0.496
Ndas_0785
Transcriptional regulator, AsnC family; COGs: COG1522 Transcriptional regulators; InterProIPR019885:IPR019887:IPR019888:IPR000485:IPR 011991:IPR011008; KEGG: tfu:Tfu_0920 AsnC family transcriptional regulator; PFAM: Transcription regulator, AsnC-type-like; SMART: Transcription regulator, AsnC-type; SPTR: C1YN68 Transcriptional regulator, AsnC family; PFAM: AsnC family.
       0.479
Your Current Organism:
Nocardiopsis dassonvillei
NCBI taxonomy Id: 446468
Other names: N. dassonvillei subsp. dassonvillei DSM 43111, Nocardiopsis dassonvillei DSM 43111, Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111, Nocardiopsis dassonvillei subsp. dassonvillei str. DSM 43111, Nocardiopsis dassonvillei subsp. dassonvillei strain DSM 43111
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.