STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ndas_1267Protein of unknown function DUF323; COGs: COG1262 conserved hypothetical protein; InterPro IPR005532; KEGG: sro:Sros_3542 hypothetical protein; PFAM: protein of unknown function DUF323; SPTR: C1YVR3 Uncharacterized conserved protein; PFAM: Formylglycine-generating sulfatase enzyme. (270 aa)    
Predicted Functional Partners:
Ndas_5226
KEGG: tfu:Tfu_0334 hypothetical protein; SPTR: C1YIP0 Putative uncharacterized protein.
  
   0.597
egtA
Glutamate/cysteine ligase family protein; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low- molecular thiol compound ergothioneine.
  
  
 0.559
egtD
Methyltransferase; Catalyzes the SAM-dependent triple methylation of the alpha- amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine; Belongs to the methyltransferase superfamily. EgtD family.
  
  
 0.558
Ndas_3470
Protein of unknown function DUF2260; COGs: COG4301 conserved hypothetical protein; InterPro IPR019257; KEGG: gvi:glr1638 hypothetical protein; PFAM: Protein of unknown function DUF2260; SPTR: C1YQ64 Uncharacterized conserved protein; PFAM: Uncharacterized conserved protein (DUF2260); TIGRFAM: probable methyltransferase.
  
  
 0.558
rnz
Ribonuclease Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family.
     
 0.481
Ndas_1097
Beta-lactamase domain protein; COGs: COG2015 Alkyl sulfatase and related hydrolase; InterPro IPR016083:IPR001279; KEGG: sco:SCO0314 secreted protein; SMART: beta-lactamase domain protein; SPTR: C1YVV5 Alkyl sulfatase-like hydrolase; PFAM: Metallo-beta-lactamase superfamily.
      
 0.469
Ndas_0445
COGs: COG0394 Protein-tyrosine-phosphatase; InterPro IPR017867:IPR000106; KEGG: tfu:Tfu_2341 protein-tyrosine-phosphatase; PFAM: Protein-tyrosine phosphatase, low molecular weight; SMART: Protein-tyrosine phosphatase, low molecular weight; SPTR: C1YLV6 Protein-tyrosine-phosphatase; PFAM: Low molecular weight phosphotyrosine protein phosphatase.
 
   
 0.449
Ndas_1266
Peptidase S9 prolyl oligopeptidase active site domain protein; COGs: COG1506 Dipeptidyl aminopeptidase/acylaminoacyl-peptidase; InterPro IPR011042:IPR001375; KEGG: mva:Mvan_5922 peptidase S9 prolyl oligopeptidase; PFAM: peptidase S9 prolyl oligopeptidase active site domain protein; SPTR: C1YVR4 Dipeptidyl aminopeptidase/acylaminoacyl peptidase; PFAM: Prolyl oligopeptidase family.
       0.409
Ndas_1268
KEGG: tfu:Tfu_1352 hypothetical protein; SPTR: C1YVR2 Putative uncharacterized protein.
       0.404
Your Current Organism:
Nocardiopsis dassonvillei
NCBI taxonomy Id: 446468
Other names: N. dassonvillei subsp. dassonvillei DSM 43111, Nocardiopsis dassonvillei DSM 43111, Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111, Nocardiopsis dassonvillei subsp. dassonvillei str. DSM 43111, Nocardiopsis dassonvillei subsp. dassonvillei strain DSM 43111
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.