STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ndas_2427Peptidase M24; COGs: COG0006 Xaa-Pro aminopeptidase; InterPro IPR007865:IPR000994:IPR001131; KEGG: tfu:Tfu_1744 Xaa-Pro aminopeptidase; PFAM: peptidase M24; peptidase M24B X-Pro dipeptidase/aminopeptidase domain protein; SPTR: C1YMA4 Xaa-Pro aminopeptidase; PFAM: Aminopeptidase P, N-terminal domain; Metallopeptidase family M24; Belongs to the peptidase M24B family. (496 aa)    
Predicted Functional Partners:
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
   0.740
Ndas_3413
COGs: COG0308 Aminopeptidase N; InterPro IPR012778:IPR014782; KEGG: tfu:Tfu_2204 aminopeptidase N; PFAM: Peptidase M1 membrane alanine aminopeptidase; SPTR: C1YQC2 Membrane alanyl aminopeptidase; TIGRFAM: aminopeptidase N; PFAM: Domain of unknown function (DUF3358); Peptidase family M1; TIGRFAM: aminopeptidase N, Streptomyces lividans type.
 
 
 0.688
Ndas_5089
Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR002869:IPR009014:IPR002880; KEGG: tfu:Tfu_2674 2-oxoglutarate ferredoxin oxidoreductase, alpha subunit; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; SPTR: C1YI76 2-oxoacid:ferredoxin oxidoreductase, alpha subunit; PFAM: domain; Pyruvate ferredoxin/flavodoxin oxidoreductase.
     
 0.678
Ndas_3767
LPPG domain protein containing protein; COGs: COG0391 conserved hypothetical protein; InterPro IPR010115:IPR002882; KEGG: tfu:Tfu_2517 LPPG:FO 2-phospho-L-lactate transferase; PFAM: protein of unknown function UPF0052 and CofD; SPTR: C1YL85 LPPG:FO 2-phospho-L-lactate transferase; TIGRFAM: LPPG domain protein containing protein; PFAM: Uncharacterised protein family UPF0052; TIGRFAM: LPPG:FO 2-phospho-L-lactate transferase.
  
  
 0.656
Ndas_4022
IMP dehydrogenase family protein; COGs: COG2070 Dioxygenase related to 2-nitropropane dioxygenase; InterPro IPR013785:IPR001093:IPR005992:IPR001412; KEGG: tfu:Tfu_2595 inosine 5-monophosphate dehydrogenase; PFAM: IMP dehydrogenase/GMP reductase; SPTR: C1YSM7 IMP dehydrogenase family protein; TIGRFAM: IMP dehydrogenase family protein; PFAM: IMP dehydrogenase / GMP reductase domain; TIGRFAM: IMP dehydrogenase family protein.
 
 
   0.594
efp
Translation elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
 
 
 0.584
rplC
50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
      
 0.581
Ndas_3768
F420 biosynthesis protein FbiB, C-terminal domain protein; COGs: COG1478 conserved hypothetical protein; InterPro IPR000415:IPR008225:IPR019943:IPR002847; KEGG: tfu:Tfu_2518 F420-0--gamma-glutamyl ligase; PFAM: protein of unknown function DUF129; nitroreductase; SPTR: C1YL84 Coenzyme F420-0 gamma-glutamyl ligase; TIGRFAM: F420 biosynthesis protein FbiB, C-terminal domain; F420-dependent oxidoreductase; PFAM: F420-0:Gamma-glutamyl ligase; Nitroreductase family; TIGRFAM: F420 biosynthesis protein FbiB, C-terminal domain; F420-0:gamma-glutamyl ligase.
  
  
 0.574
orn
Exonuclease RNase T and DNA polymerase III; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family.
  
     0.535
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 
 0.532
Your Current Organism:
Nocardiopsis dassonvillei
NCBI taxonomy Id: 446468
Other names: N. dassonvillei subsp. dassonvillei DSM 43111, Nocardiopsis dassonvillei DSM 43111, Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111, Nocardiopsis dassonvillei subsp. dassonvillei str. DSM 43111, Nocardiopsis dassonvillei subsp. dassonvillei strain DSM 43111
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