STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ndas_2874TrkA-N domain protein; COGs: COG0569 K+ transport systems NAD-binding component; InterPro IPR016040:IPR003148:IPR006037:IPR006036; KEGG: tfu:Tfu_1928 putative potassium transporter; PFAM: TrkA-N domain protein; TrkA-C domain protein; SPTR: C1YJX2 K+ transport system, NAD-binding component; PFAM: TrkA-N domain; TrkA-C domain. (242 aa)    
Predicted Functional Partners:
Ndas_2875
TrkA-N domain protein; COGs: COG0569 K+ transport systems NAD-binding component; InterPro IPR016040:IPR003148:IPR006037:IPR006036; KEGG: tfu:Tfu_1929 putative potassium uptake protein; PFAM: TrkA-N domain protein; TrkA-C domain protein; SPTR: C1YJX1 K+ transport system, NAD-binding component; PFAM: TrkA-N domain; TrkA-C domain.
 
  
 0.965
Ndas_0524
H(+)-transporting two-sector ATPase; COGs: COG0168 Trk-type K+ transport systems membrane components; InterPro IPR003445; KEGG: tfu:Tfu_2302 putative cation transporter; PFAM: cation transporter; PRIAM: H(+)-transporting two-sector ATPase; SPTR: C1YLM7 Trk-type K+ transport system, membrane component; PFAM: Cation transport protein.
  
 
 0.739
Ndas_1634
H(+)-transporting two-sector ATPase; COGs: COG0168 Trk-type K+ transport systems membrane components; InterPro IPR003445; KEGG: svi:Svir_36680 trk-type K+ transport system, membrane component; PFAM: cation transporter; PRIAM: H(+)-transporting two-sector ATPase; SPTR: C1YJK6 Trk-type K+ transport system, membrane component; PFAM: Cation transport protein; TIGRFAM: potassium uptake protein, TrkH family.
  
 
 0.739
Ndas_0855
Fmu (Sun) domain protein; COGs: COG0144 tRNA and rRNA cytosine-C5-methylase; InterPro IPR018314:IPR006027:IPR001678; KEGG: tfu:Tfu_1076 putative RNA-binding Sun protein; PFAM: Fmu (Sun) domain protein; NusB/RsmB/TIM44; SPTR: C1YQP2 tRNA/rRNA cytosine-C5-methylase; PFAM: NOL1/NOP2/sun family; NusB family; TIGRFAM: ribosomal RNA small subunit methyltransferase RsmB; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
  
   0.675
Ndas_2873
RNA methyltransferase, TrmA family; COGs: COG2265 SAM-dependent methyltransferase related to tRNA (uracil-5-)-methyltransferase; InterPro IPR010280:IPR001566:IPR002792:IPR016027; KEGG: tfu:Tfu_1927 23S rRNA methyltransferase/RumA; PFAM: deoxyribonuclease/rho motif-related TRAM; (Uracil-5)-methyltransferase; SPTR: C1YJX3 23S rRNA m(5)U-1939 methyltransferase; TIGRFAM: RNA methyltransferase, TrmA family; PFAM: TRAM domain; tRNA (Uracil-5-)-methyltransferase; TIGRFAM: 23S rRNA (uracil-5-)-methyltransferase RumA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5 [...]
       0.614
Ndas_3798
Molybdopterin biosynthesis MoaE protein; COGs: COG0314 Molybdopterin converting factor large subunit; InterPro IPR003448; KEGG: tfu:Tfu_0538 molybdopterin synthase subunit MoaE; PFAM: molybdopterin biosynthesis MoaE protein; SPTR: C1YL55 Molybdopterin synthase subunit MoaE; PFAM: MoaE protein.
   
    0.609
Ndas_4370
Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; COGs: COG1587 Uroporphyrinogen-III synthase; InterProIPR000878:IPR003754:IPR003043:IPR014777:IPR 014776; KEGG: tfu:Tfu_2731 uroporphyrinogen-III C-methyltransferase / uroporphyrinogen-III synthase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; SPTR: C1YGP0 Uroporphyrinogen-III synthase; uroporphyrinogen-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD.
  
    0.567
Ndas_2178
COGs: COG1587 Uroporphyrinogen-III synthase; InterPro IPR003754:IPR001867:IPR011991:IPR016032; KEGG: sco:SCO2958 bifunctional uroporphyrinogen-III synthetase/response regulator domain protein; PFAM: Uroporphyrinogen III synthase HEM4; transcriptional regulator domain protein; SPTR: C1YWH3 Uroporphyrinogen-III synthase; PFAM: Transcriptional regulatory protein, C terminal; Uroporphyrinogen-III synthase HemD.
  
    0.555
pup
Protein of unknown function DUF797; Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
  
     0.456
pafA
Protein of unknown function DUF245 domain protein; Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side- chain amino group of a substrate lysine.
  
     0.442
Your Current Organism:
Nocardiopsis dassonvillei
NCBI taxonomy Id: 446468
Other names: N. dassonvillei subsp. dassonvillei DSM 43111, Nocardiopsis dassonvillei DSM 43111, Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111, Nocardiopsis dassonvillei subsp. dassonvillei str. DSM 43111, Nocardiopsis dassonvillei subsp. dassonvillei strain DSM 43111
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.