STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ndas_3599Conserved hypothetical protein; COGs: COG0421 Spermidine synthase; KEGG: tfu:Tfu_0771 hypothetical protein; SPTR: C1YQX9 Putative uncharacterized protein; PFAM: Spermine/spermidine synthase. (289 aa)    
Predicted Functional Partners:
proS
prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...]
  
  
 0.548
Ndas_3600
COGs: COG4585 Signal transduction histidine kinase; InterPro IPR003594:IPR011712; KEGG: tfu:Tfu_0768 putative two-component system sensor kinase; PFAM: histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; SPTR: C1YQX8 Signal transduction histidine kinase, COG4585; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
       0.528
Ndas_3601
Two component transcriptional regulator, LuxR family; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR011006:IPR001789:IPR000792:IPR011991; KEGG: tfu:Tfu_0767 LuxR response regulator receiver; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; SPTR: C1YQX7 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family.
       0.528
Ndas_5015
KEGG: tfu:Tfu_2700 hypothetical protein; SPTR: C1YIE9 Putative uncharacterized protein.
  
    0.447
Ndas_0376
Type III restriction protein res subunit; COGs: COG1061 DNA or RNA helicase of superfamily II; InterProIPR014021:IPR001650:IPR014001:IPR003593:IPR 006935; KEGG: tfu:Tfu_2381 ATPase; PFAM: type III restriction protein res subunit; SMART: DEAD-like helicase; AAA ATPase; SPTR: C1YH32 DNA/RNA helicase, superfamily II; PFAM: Type III restriction enzyme, res subunit.
  
     0.417
Your Current Organism:
Nocardiopsis dassonvillei
NCBI taxonomy Id: 446468
Other names: N. dassonvillei subsp. dassonvillei DSM 43111, Nocardiopsis dassonvillei DSM 43111, Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111, Nocardiopsis dassonvillei subsp. dassonvillei str. DSM 43111, Nocardiopsis dassonvillei subsp. dassonvillei strain DSM 43111
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