Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACZ23102.1Dihydroneopterin aldolase/2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (1211 aa)    
Predicted Functional Partners:
ACZ23103.1
Dihydropteroate synthase; PFAM: Pterin binding enzyme; TIGRFAM: dihydropteroate synthase.
 
  
 0.994
folE
PFAM: GTP cyclohydrolase I; TIGRFAM: GTP cyclohydrolase I.
 
  
 0.994
ACZ22498.1
Dihydropteroate synthase; PFAM: Pterin binding enzyme; TIGRFAM: dihydropteroate synthase.
 
  
 0.972
panC
Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
 
   
 0.859
panD
L-aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
       0.804
ACZ23098.1
Uncharacterized conserved protein; PFAM: Rossmann-like domain; Domain of unknown function (DUF2520).
       0.804
ACZ23099.1
Predicted membrane protein; PFAM: Bacterial membrane flanked domain.
       0.804
ACZ23100.1
Uncharacterized conserved protein; PFAM: Bacterial membrane flanked domain.
       0.804
ACZ23101.1
Hypothetical protein.
       0.804
ACZ23095.1
L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
     
 0.801
Your Current Organism:
Sanguibacter keddieii
NCBI taxonomy Id: 446469
Other names: S. keddieii DSM 10542, Sanguibacter keddieii DSM 10542, Sanguibacter keddieii str. DSM 10542, Sanguibacter keddieii strain DSM 10542
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