STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Snas_1519PFAM: isochorismatase hydrolase; KEGG: mes:Meso_3207 isochorismatase hydrolase. (189 aa)    
Predicted Functional Partners:
Snas_1520
Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.
 
 0.998
Snas_0479
PFAM: Silent information regulator protein Sir2; KEGG: sfu:Sfum_3557 silent information regulator protein Sir2.
  
 0.909
Snas_2614
PFAM: Silent information regulator protein Sir2; KEGG: bbt:BBta_4037 putative transcriptional regulatory Sir2-family protein.
  
 0.909
Snas_6136
TIGRFAM: purine nucleoside phosphorylase; PFAM: purine or other phosphorylase family 1; KEGG: vvy:VVA0354 purine nucleoside phosphorylase.
    
  0.900
Snas_5299
KEGG: afw:Anae109_0595 carbohydrate kinase; TIGRFAM: carbohydrate kinase, thermoresistant glucokinase family; PFAM: shikimate kinase.
      0.890
rpsL
Ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
  
  
 0.728
Snas_2497
PFAM: short-chain dehydrogenase/reductase SDR; KEGG: mxa:MXAN_6034 enoyl-(acyl carrier protein) reductase.
     
 0.710
gyrA
DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
      
 0.708
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
      
 0.708
katG
Catalase/peroxidase HPI; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily.
      
 0.708
Your Current Organism:
Stackebrandtia nassauensis
NCBI taxonomy Id: 446470
Other names: S. nassauensis DSM 44728, Stackebrandtia nassauensis DSM 44728, Stackebrandtia nassauensis str. DSM 44728, Stackebrandtia nassauensis strain DSM 44728
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