STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
Snas_2497PFAM: short-chain dehydrogenase/reductase SDR; KEGG: mxa:MXAN_6034 enoyl-(acyl carrier protein) reductase. (260 aa)    
Predicted Functional Partners:
Snas_4811
3-oxoacyl-(acyl-carrier-protein) synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
 
  
 0.975
Snas_0213
PFAM: carboxyl transferase; acetyl-CoA carboxylase alpha subunit; KEGG: acetyl-coA carboxylase; K01959 pyruvate carboxylase subunit A.
 
  
 0.974
Snas_4808
KEGG: cja:CJA_1675 malonyl CoA-acyl carrier protein transacylase.
 
  
 0.966
fabH
3-oxoacyl-(acyl-carrier-protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
 
  
 0.960
Snas_2496
TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) reductase; PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; NAD-dependent epimerase/dehydratase; KEGG: prw:PsycPRwf_0457 3-oxoacyl-(acyl-carrier- protein) reductase.
 
  
 0.893
Snas_1481
PFAM: 4'-phosphopantetheinyl transferase; KEGG: mrd:Mrad2831_0013 4'-phosphopantetheinyl transferase; Belongs to the P-Pant transferase superfamily.
  
    0.799
Snas_4133
PFAM: Acyl transferase; Beta-ketoacyl synthase; Erythronolide synthase docking; Thioesterase; phosphopantetheine-binding; KEGG: eca:ECA0603 type I polyketide synthase.
  
 
 0.770
gyrA
DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
  
  
 0.718
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
       0.711
Snas_1519
PFAM: isochorismatase hydrolase; KEGG: mes:Meso_3207 isochorismatase hydrolase.
     
 0.710
Your Current Organism:
Stackebrandtia nassauensis
NCBI taxonomy Id: 446470
Other names: S. nassauensis DSM 44728, Stackebrandtia nassauensis DSM 44728, Stackebrandtia nassauensis str. DSM 44728, Stackebrandtia nassauensis strain DSM 44728
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