STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (388 aa)    
Predicted Functional Partners:
aroK
3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
  
 0.998
aroA
3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
 
 0.997
Snas_6087
TIGRFAM: chorismate mutase; PFAM: Chorismate mutase; KEGG: ppd:Ppro_1345 chorismate mutase.
  
 
 0.980
Snas_0686
TIGRFAM: anthranilate synthase; PFAM: Chorismate binding-like; glutamine amidotransferase class-I; KEGG: scl:sce5044 anthranilate synthase.
 
 
 0.974
Snas_3875
PFAM: Shikimate dehydrogenase substrate binding domain protein; Shikimate/quinate 5-dehydrogenase; KEGG: cak:Caul_5013 shikimate 5-dehydrogenase; Belongs to the shikimate dehydrogenase family.
 
  
 0.959
Snas_0236
PFAM: Prephenate dehydrogenase; 6-phosphogluconate dehydrogenase NAD-binding; KEGG: nmu:Nmul_A2195 prephenate dehydrogenase.
 
 
 0.951
Snas_3736
PFAM: Chorismate binding-like; KEGG: afw:Anae109_1629 para-aminobenzoate synthase, subunit I.
 
 
 0.946
Snas_6135
TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: esa:ESA_04373 hypothetical protein.
 
 
 0.931
Snas_4515
TIGRFAM: isochorismate synthase; PFAM: Chorismate binding-like; KEGG: mxa:MXAN_3646 isochorismate synthase DhbC.
 
  
 0.928
Snas_0552
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: afw:Anae109_1891 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein.
   
 
 0.926
Your Current Organism:
Stackebrandtia nassauensis
NCBI taxonomy Id: 446470
Other names: S. nassauensis DSM 44728, Stackebrandtia nassauensis DSM 44728, Stackebrandtia nassauensis str. DSM 44728, Stackebrandtia nassauensis strain DSM 44728
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