| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Xcel_0002 | Xcel_0003 | Xcel_0002 | Xcel_0003 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | TIGRFAM: 6-phosphogluconate dehydrogenase, decarboxylating; PFAM: 6-phosphogluconate dehydrogenase NAD-binding; 6-phosphogluconate dehydrogenase domain protein; KEGG: dde:Dde_3470 6-phosphogluconate dehydrogenase- like protein. | 0.699 |
| Xcel_0002 | Xcel_0005 | Xcel_0002 | Xcel_0005 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | PFAM: protein of unknown function DUF721; KEGG: protein of unknown function DUF721. | 0.704 |
| Xcel_0002 | Xcel_0008 | Xcel_0002 | Xcel_0008 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Putative FHA domain containing protein; KEGG: hypothetical protein. | 0.725 |
| Xcel_0002 | Xcel_2131 | Xcel_0002 | Xcel_2131 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Hypothetical protein. | 0.447 |
| Xcel_0002 | Xcel_2208 | Xcel_0002 | Xcel_2208 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III delta; KEGG: noc:Noc_2663 DNA polymerase III, delta subunit. | 0.991 |
| Xcel_0002 | gyrB | Xcel_0002 | Xcel_0006 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.916 |
| Xcel_0002 | nucS | Xcel_0002 | Xcel_2445 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Protein of unknown function DUF91; Cleaves both 3' and 5' ssDNA extremities of branched DNA structures; Belongs to the NucS endonuclease family. | 0.762 |
| Xcel_0002 | recF | Xcel_0002 | Xcel_0004 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family. | 0.963 |
| Xcel_0003 | Xcel_0002 | Xcel_0003 | Xcel_0002 | TIGRFAM: 6-phosphogluconate dehydrogenase, decarboxylating; PFAM: 6-phosphogluconate dehydrogenase NAD-binding; 6-phosphogluconate dehydrogenase domain protein; KEGG: dde:Dde_3470 6-phosphogluconate dehydrogenase- like protein. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.699 |
| Xcel_0003 | Xcel_0005 | Xcel_0003 | Xcel_0005 | TIGRFAM: 6-phosphogluconate dehydrogenase, decarboxylating; PFAM: 6-phosphogluconate dehydrogenase NAD-binding; 6-phosphogluconate dehydrogenase domain protein; KEGG: dde:Dde_3470 6-phosphogluconate dehydrogenase- like protein. | PFAM: protein of unknown function DUF721; KEGG: protein of unknown function DUF721. | 0.690 |
| Xcel_0003 | recF | Xcel_0003 | Xcel_0004 | TIGRFAM: 6-phosphogluconate dehydrogenase, decarboxylating; PFAM: 6-phosphogluconate dehydrogenase NAD-binding; 6-phosphogluconate dehydrogenase domain protein; KEGG: dde:Dde_3470 6-phosphogluconate dehydrogenase- like protein. | DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family. | 0.706 |
| Xcel_0005 | Xcel_0002 | Xcel_0005 | Xcel_0002 | PFAM: protein of unknown function DUF721; KEGG: protein of unknown function DUF721. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.704 |
| Xcel_0005 | Xcel_0003 | Xcel_0005 | Xcel_0003 | PFAM: protein of unknown function DUF721; KEGG: protein of unknown function DUF721. | TIGRFAM: 6-phosphogluconate dehydrogenase, decarboxylating; PFAM: 6-phosphogluconate dehydrogenase NAD-binding; 6-phosphogluconate dehydrogenase domain protein; KEGG: dde:Dde_3470 6-phosphogluconate dehydrogenase- like protein. | 0.690 |
| Xcel_0005 | Xcel_0008 | Xcel_0005 | Xcel_0008 | PFAM: protein of unknown function DUF721; KEGG: protein of unknown function DUF721. | Putative FHA domain containing protein; KEGG: hypothetical protein. | 0.724 |
| Xcel_0005 | Xcel_1290 | Xcel_0005 | Xcel_1290 | PFAM: protein of unknown function DUF721; KEGG: protein of unknown function DUF721. | PFAM: protein of unknown function YGGT; KEGG: bbk:BARBAKC583_0327 YGGT family protein. | 0.644 |
| Xcel_0005 | Xcel_2131 | Xcel_0005 | Xcel_2131 | PFAM: protein of unknown function DUF721; KEGG: protein of unknown function DUF721. | Hypothetical protein. | 0.617 |
| Xcel_0005 | Xcel_2208 | Xcel_0005 | Xcel_2208 | PFAM: protein of unknown function DUF721; KEGG: protein of unknown function DUF721. | TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III delta; KEGG: noc:Noc_2663 DNA polymerase III, delta subunit. | 0.657 |
| Xcel_0005 | Xcel_2736 | Xcel_0005 | Xcel_2736 | PFAM: protein of unknown function DUF721; KEGG: protein of unknown function DUF721. | PFAM: glycosyl transferase family 39; KEGG: mca:MCA2192 dolichyl-phosphate-mannose- protein mannosyltransferase family protein. | 0.719 |
| Xcel_0005 | gyrB | Xcel_0005 | Xcel_0006 | PFAM: protein of unknown function DUF721; KEGG: protein of unknown function DUF721. | DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.644 |
| Xcel_0005 | nucS | Xcel_0005 | Xcel_2445 | PFAM: protein of unknown function DUF721; KEGG: protein of unknown function DUF721. | Protein of unknown function DUF91; Cleaves both 3' and 5' ssDNA extremities of branched DNA structures; Belongs to the NucS endonuclease family. | 0.647 |