STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Xcel_0160Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (191 aa)    
Predicted Functional Partners:
Xcel_2083
PFAM: Phosphoglycerate mutase; ribonuclease H; KEGG: mxa:MXAN_5728 ribonuclease H.
  
 
 0.916
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
      0.797
Xcel_0159
KEGG: scl:sce7864 putative DNA-3-methyladenine glycosidase.
       0.795
Xcel_1173
Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
   
 
 0.745
Xcel_0229
Hypothetical protein.
 
      0.590
Xcel_1391
PFAM: GCN5-related N-acetyltransferase; KEGG: scl:sce6328 hypothetical protein.
 
      0.563
Xcel_2084
PFAM: protein of unknown function DUF164; KEGG: glo:Glov_0682 protein of unknown function DUF164.
  
  
 0.557
Xcel_0158
PFAM: fatty acid desaturase; KEGG: cak:Caul_2941 fatty acid desaturase.
       0.552
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
 
 
 
 0.534
Xcel_0161
PFAM: protein of unknown function DUF125 transmembrane; KEGG: afw:Anae109_0752 hypothetical protein.
       0.532
Your Current Organism:
Xylanimonas cellulosilytica
NCBI taxonomy Id: 446471
Other names: X. cellulosilytica DSM 15894, Xylanimonas cellulosilytica DSM 15894, Xylanimonas cellulosilytica str. DSM 15894, Xylanimonas cellulosilytica strain DSM 15894
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