STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cobBSilent information regulator protein Sir2; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class II subfamily. (305 aa)    
Predicted Functional Partners:
Xcel_0430
PFAM: histone deacetylase superfamily; KEGG: bsu:BSU29710 acetoin dehydrogenase.
    
 
 0.791
Xcel_0786
PFAM: UvrD/REP helicase; HRDC domain protein; SMART: HRDC domain protein; KEGG: gsu:GSU3411 ATP-dependent DNA helicase PcrA, putative.
  
 
 0.757
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
    
 0.710
Xcel_2595
TIGRFAM: cell envelope-related function transcriptional attenuator, LytR/CpsA family; PFAM: cell envelope-related transcriptional attenuator; KEGG: bcy:Bcer98_3735 cell envelope-related transcriptional attenuator.
  
    0.696
Xcel_0693
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
  
  
 0.687
Xcel_1350
Transcriptional regulator, winged helix family; PFAM: transcriptional activator domain; transcriptional regulator domain protein; KEGG: bac:BamMC406_5609 transcriptional regulator.
   
    0.687
Xcel_1356
Putative transcriptional regulator; PFAM: Helix-turn-helix type 11 domain protein; regulatory protein ArsR; KEGG: vvy:VV3021 transcriptional regulator.
   
    0.687
Xcel_2226
PFAM: iron dependent repressor; regulatory protein GntR HTH; FeoA family protein; SMART: iron dependent repressor; KEGG: tcx:Tcr_0904 iron dependent repressor.
  
    0.687
Xcel_2242
TIGRFAM: transcriptional regulator, ArgP family; PFAM: regulatory protein LysR; KEGG: oriC; transcriptional regulator LysR family; K05596 LysR family transcriptional regulator, chromosome initiation inhibitor.
   
    0.687
Xcel_2296
Glutamate dehydrogenase (NADP(+)); PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; KEGG: swi:Swit_0418 glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 0.678
Your Current Organism:
Xylanimonas cellulosilytica
NCBI taxonomy Id: 446471
Other names: X. cellulosilytica DSM 15894, Xylanimonas cellulosilytica DSM 15894, Xylanimonas cellulosilytica str. DSM 15894, Xylanimonas cellulosilytica strain DSM 15894
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