STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Xcel_0343PFAM: phosphoesterase PA-phosphatase related; SMART: phosphoesterase PA-phosphatase related; KEGG: bpa:BPP3396 hypothetical protein. (306 aa)    
Predicted Functional Partners:
rplF
Ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
   
 0.767
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
    0.684
Xcel_0451
PFAM: AMP-dependent synthetase and ligase; KEGG: scl:sce3015 O-succinylbenzoate-CoA ligase.
    
 0.681
Xcel_1973
PFAM: AMP-dependent synthetase and ligase; KEGG: sfu:Sfum_0108 AMP-dependent synthetase and ligase.
    
 0.681
Xcel_3072
KEGG: rru:Rru_A2517 AMP-dependent synthetase and ligase.
    
 0.681
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
   0.667
Xcel_2424
KEGG: similar to hedgehog protein.
  
     0.549
Xcel_2819
Hypothetical protein; KEGG: mch:Mchl_4744 putative superfamily I DNA and RNA helicase protein.
  
     0.538
Xcel_2617
PFAM: Aldehyde Dehydrogenase; Proline dehydrogenase; KEGG: dal:Dalk_3943 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
   
 0.529
Xcel_1249
Hypothetical protein.
  
     0.489
Your Current Organism:
Xylanimonas cellulosilytica
NCBI taxonomy Id: 446471
Other names: X. cellulosilytica DSM 15894, Xylanimonas cellulosilytica DSM 15894, Xylanimonas cellulosilytica str. DSM 15894, Xylanimonas cellulosilytica strain DSM 15894
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